1. Infection Unit 12 Adonis K. Lomibao, R.N. 12/19/11

3. Objectives Spell & Define key terms Identify most common microbes & characteristics List links in chain of infection List the ways infectious disease are spread Name & describe 5 serious diseases

4. Objectives Cont. Identify cause of important infectious disease Define spores & explain how they differ from other pathogens Describe common treatments for infectious disease. List natural body defenses against infection Explain why patients are at risk for infection.

5. Introduction Organisms-living beings Microorganisms or microbes-tiny organisms Nonpathogens-microbes that do not cause disease Pathogens- disease causing microbes -Grow best at body temp, limited light, moisture,food supply, & oxygen. Infection- pathogens invade the body & cause disease.

6. Microbes 4 types -Bacteria -Viruses -Fungi -Protozoa

7. Bacteria Simple one-celled organisms Named according to shapes & arrangement Shapes: -Coccus- round or spherical -Bacillus-straight rod -Spirillum-spiral, corkscrew,slightly curved

8. Bacteria Cont. Arrangements: -single -pairs:diplo- -chains:strepto- -clusters:staphylo- Colonies-groups of growing bacteria

9. Fungi 2 kinds: -yeast:single cell budding forms of a fungus. Can affect mouth, skin, & feet -molds:can cause infections in the lung Parasite: an organism that lives in or on another organism without benefiting the host. Immuno-suppressed patients at risk

10. Virus The smallest microbe Come in a variety of shapes Classified by: -type of DNA or RNA -clinical properties Common viruses include: Hepatitis,Herpes,HIV/AIDS,chickenpox, influenza, common cold,p.156

11. Protozoa Once-celled organisms that live on living matter Classified by how the move...i.e. Whiplike tails, hairlike projections. i.e. Malaria S&S:Diarrhea, Dysentery(lower bowel infection), encephalitis

12. The Chain of Infection Certain conditions exist for infection to occur COI Includes: -Causative agent:pathogen that causes disease -Reservoir or source: where the pathogen can live & reproduce -Portal of exit: manner in which the pathogen leaves the body

13. COI Cont. Method or mode of transmission:manner in which the pathogen is carried to another person Portal of Entry: manner in which the pathogen enters the body Susceptible host: a person who will become ill from the entry of pathogens into the body Object of Infection control is to DISRUPT the chain of infection!!

14. Causative agent Microorganism that can produce the disease in humans Most common causes: -Bacteria -Viruses -Fungi -Protozoa

15. Reservoir or source Where pathogens can survive May or may-not multiply in reservoir Four common reservoirs: -Humans -Insects & animals -Environment -Fomites:objects that can be contaminated with infectious material that contains the microbe.

16. Human Reservoirs 2 types; -Cases:people with acute illness with S&S -Carriers: persons who can give a disease to others. May not have S&S or know of infections.

17. Portals of Entry Organisms enter through: -breaks in skin or mucous membranes -respiratory tract -genitourinary tract -gastrointestinal tract -circulatory system -transplacental

18. Portals of Exit Leave the reservoir of host through body secretions POE Include: -excretions or resp. tract or genital tract -draining wounds -urine -feces -blood & body fluids -Saliva & Tears

19. Transmission of Disease Spread of infectious organisms may happen in 3 ways: -Airborne Transmission -Droplet Transmission -Contact Transmission -Vector Transmission

20. Host The person who harbors infectious organisms. Person does not have enough resistance to agent Infection develops when organism penetrates the body, begins to multiply, & causes damage Risk factors are conditions that indicate a problem may develop.

21. Types of Infections Local: confined to one area..i.e. Boil or abscess Generalized: i.e. pneumonia in the lungs Systemic: widespread through bloodstream

23. Body Flora Microbes that live in and on our body surfaces Healthy individuals lives in harmony with flora Balance may be disturbed by: -pathogens -normal flora that become pathogenic -flora from on body area to another -drugs that upset balance and allow one to flourish

24. How Pathogens Affect the Body Microbes act in different ways to produce disease: -Attack & destroy cells they invade -produce toxins that harm the body -cause sensitivity responses called allergies

25. Body Defenses Intact skin Mucous membranes-sticky & trap foreign materials Cilia-propel mucus out of body Coughing & sneezing Hydrochloric acid Tears

26. Internal Defenses Fever Phagocytes Inflammation Temperature Immune response

27. Immunity The ability to fight of disease caused by microbes Antigen- pathogenic microbe that enters the body Antibodies- provide immunity to disease caused by that antigen Immunization: Vaccines protect against specific pathogens Immunosupression: the body's immune system is inadequate...more likely to develop infections.

28. Bacterial Infections Diagnositic: Culture & Sensitivity Antibiotic-antibacterial drug. Common bacterial infections include: -MRSA & VRE -Tuberculosis -Streptococcus A -Escherichia coli -Pseudomembranous Colitis(C. Diff)

29. Spores Microscopic reproductive bodies that are responsible for the spread of some diseases. Can survive in a dormant form until conditions are ideal for reproduction Difficult to eliminate Examples: -Norovirus -C. Difficile

30. Viral Infections Examples: -Shingles -Influenza -AIDS -Hantavirus -Sever Acute Resp. Syndrome -Smallpox

31. Parasites Survive by feeding off another human or animal Examples: -Head Lice:spread by direct contact.--Nits(eggs) -Scabies:caused my microscopic mite.Spread by in/direct contact -Bedbugs:bites cause painful rash

32. Self-Care Healthy diet Get enough sleep Keep your body clean Live in a clean environment Avoid smoking & substance abuse Learn how to cope with stress