1. Cross-border clusters and business cooperation: BioValley, a case study Mona BOYE Scientific Coordinator and Business Development Thursday 23 April 2015

2. Alsace BioValley “Cross-border clusters and business cooperation Making the most of cross-border clusters for business cooperation: BioValley, a case study” Student Worl Forum, Strasbourg April 22nd 2015

3. www.alsace-biovalley.com 3

4. 4 Life Sciences & Healthcare industry world leaders:

5. www.alsace-biovalley.com 5 Welcome to Als ce, in the heart of the French-German-Swiss BioValley! An access to 300 million EU consumers within a 900 Km radius! Discover trinational Excellence in Health innovation & business : 50 000 employees in Life Sciences 3 universities (Strasbourg, Basel, Fribourg) ranked in the top 100 of the world's best universities in Life Sciences (source: 2014 Shangaï ranking) 6 Nobel Prizes in Life Sciences (source: www.biovalley.com) 700 Life Sciences companies within 200 km radius (source: Alsace BioValley Efficy + Venture Valuation database)

6. www.alsace-biovalley.com 6 8 280 km 2 - 1,8 million inhabitants 8 th French region for the weight of its public research (429 M€ en 2011) (source : AAA Doc SRDEII – Ministère de l’enseignement supérieur et de la recherche) 93 th European region (on 262) for competitivity, 2 e French region after Ile de France region (source : AAA Doc SRDEII – Ministère de l’enseignement supérieur et de la recherche) 3 rd French region for innovation ((source : www.alsace.com) Alsace region is also: Welcome to Als ce, in the heart of the French-German-Swiss BioValley!

7. www.alsace-biovalley.com 7 Source : Alsace BioValley (Efficy - 2014) + Conectus Alsace 2014 Alsace focus: Life Sciences main figures France's smallest region (8 980 km 2 ), Alsace is home to no less than 250 Life Sciences companies: 100 Companies: - 84 % services - 16 % R&D & production 270 Research teams 150 Companies: - 50 % R&D - 38 % services - 12 % production 105 Research teams Alsace BioValley counts over 85 industrial members

8. www.alsace-biovalley.com 8 Healthcare Alsatian excellence in Industry !

9. www.alsace-biovalley.com 9 In the French-German-Swiss BioValley : many Life Sciences world leaders within a 200 km radius! Source: www.biovalley.com - 2014

10. www.alsace-biovalley.com 10 Alsace focus: SME’s & start’ups, only the best in Alsace! Drugs Discovery Just a few examples of local talents… Isotope chemistry Robotics Bioartificial devices Stem cells Cell therapy Neurosciences CRO Physical chemistry Cardio devices Diagnostic Manufacturing Biosimulation & new drugs Medical devices Intraocular lenses Implants Biosimulation 3D Medical Model Drugs Discovery

11. www.alsace-biovalley.com 11 Healthcare Alsatian excellence in Sciences!

12. www.alsace-biovalley.com 12 In the French-German-Swiss BioValley : many world-class experts to the hand! NOBEL PRIZE In 1989 Michael Reth joined Nobel laureate George Köhler’s laboratory at the Max Planck Institute and later on was appointed Chair of Molecular Immunology at the University of Freiburg. He was awarded the Gottfried Willhelm Leibniz Prize of the German Research Foundation in 1995 and the EFIS-Schering-Plough European Immunology Prize in 2009. In 2012, Michael Reth was awarded an advanced grant by the European Research Council (ERC). In 2014 he was awarded by the Paul Ehrlich and Ludwig Darmstaedter Prize. Prof. Michael RETH Immunology Source: www.biovalley.com - 2014

13. www.alsace-biovalley.com 13 In the French-German-Swiss BioValley: performing TTOs! Just a few examples… Source: www.biovalley.com - 2014

14. www.alsace-biovalley.com 14 A Strategic focus on 7 forward-looking scientific sectors CHEMISTRY & BIOLOGY RNA & RIBOSOMES DRUG DELIVERY MEDICAL ROBOTICS MINI-INVASIVE SURGERY SIMULATION AND MODELING TOOLS IMPLANTABLE MEDICAL DEVICES

15. www.alsace-biovalley.com 15 How to foster business for Alsacian companies!

16. www.alsace-biovalley.com 16 Boosting the growth of our companies 3 corporate services for driving innovation & business! Development of innovative collaborative projects Coaching to fund raising Watching out for new business in France and International BUSINESSFUND RAISINGMARKET INNOVATION

17. www.alsace-biovalley.com 17 Our corporate services - 1 Are you looking to fund and develop an innovative Healthcare product? Alsace BioValley delivers: Partner search Funding search Business plan Assessment of scientific and business potential Consortium agreements Legal advice Industrial property rights MARKET INNOVATION

18. www.alsace-biovalley.com 18 Local support up to 45 % for a company, driving its research in France FUI (Fond Unique Interministériel) up to 45 % for a company driving its research in France Several programs from BPI France (French Public Investment bank) EuroTransBio up to 45 % for a company driving its research in France Our corporate services - 1 Public cofinancing for collaboration projects MARKET INNOVATION programs to support your collaboration project:

19. www.alsace-biovalley.com 19 Our corporate services - 2 Are you looking to raise funds? Alsace BioValley delivers: Business plan Marketing guidance Financial engineering Presentation pitch exercising Connecting with investors FUND RAISING

20. www.alsace-biovalley.com 20 Our corporate services - 3 Are you watching out for new business? Alsace BioValley delivers: Networking events and organisation of B2B Shared business developer Exploring markets International calls for projects Joint booth at international exhibitions Promotion & visibility BUSINESS

21. www.alsace-biovalley.com 21 2010 with Consortium Québecois on Drug Discovery/ QUEBEC 4 calls launched 2013 with Massachusetts Life Science Center / USA : 2 calls launched Memorandum of Understandings 2014 Japan, JBA Germany, BIOPRO Our international development : Funding bilateral collaborative research projects between companies.

22. www.alsace-biovalley.com 22 Contact our 2 Life Sciences Business- developpers! Germany & Switzerland Europe & International mona.boye@alsace-biovalley.com agnes.legoll@alsace-biovalley.com Looking for new projects or business in Life Sciences? Meet us!

23. www.alsace-biovalley.com 23 All informations about Alsace region & Alsace BioValley cluster! All informations about the French-German-Swiss BioValley & its Health players ! Discover our trinational BioValley companies database! Keep the contact: surf on our websites & join us on Linkedin! www.alsace-biovalley.com/en www.biovalley.com Discover our member database! Thank you!

24. New routes for teaching in the Upper Rhine Basin Jean-Marc JELTSCH Vice-President in charge of industrial partnerships University of Strasbourg Thursday 23 April 2015