1. NERSA Public Hearings Devan Pillay Consumer Health Division Head of Engineering: Africa 20 January 2010 South Africa

4. The Problem… 0.51.050.7 1.5 0.5 201020112012

5. Our response… 2009

6. Elephantiasis Relatively uncommon late complication of filariasis Death of worms causes calcification and obstruction Recurrent secondary bacterial and fungal infections play a very important role

7. A Disease Of Devastating Proportions 80 endemic countries 1.2 billion people at risk 120 million people affected

8. An infection of children 1 million children infected each year Children become infected when very young but usually appear healthy The latency period is long: visible symptoms present in puberty Diagnostic tools can detect early infection Of all LF sufferers, children will benefit most from the elimination programme

9. GSK’s Commitment The industry’s largest donation programme 5 -7 billion tablets of albendazole over 20+ years Providing valuable financial support to essential, operational research

10. Progress 1013 million albendazole tablets to 48 countries by end of 2008

12. Albendazole LF - pack of 100 Tablets2010 Nashik (£) Cape Town (£) Total Cost of Production1.201.321.35 % Difference in cost against Nashik 1013

13. In Summary  Above inflationary increases make companies less competitive in the market place.  Gradual ‘Leakage’ of jobs to lower cost structured economies  Alternative funding mechanism to the increase needs to be sought  Defeats the work done in the last 10-12 years to bring us where we are today…

14. What did you do to save energy today? Questions ??