1. The Smart Vivarium Physiologic and Environmental Monitoring of Rodents

2. The Smart Vivarium Management Basic Well Being/Health Reproduction Biosecurity Management Basic Well Being/Health Reproduction Biosecurity

3. Management Census Measurement Supply Waste Identification Environment Census Measurement Supply Waste Identification Environment

4. Census Measurements Per Animal Per Cage Per Room Per Animal Per Cage Per Room

5. SupplySupply Food Food Water Water Bedding Bedding Enrichment Enrichment Caging materials Caging materials

6. Waste Food Water Bedding Housing materials Metabolic products Ammonia Heat - humidity Feces

7. The Environment Room Air Light Humidity Light intensity Location in room Equipment Percent of time cage open

8. Identification

9. Basic Well Being Body composition Activity Drinking Eating Urination Defecation Physiologic Parameters Body composition Activity Drinking Eating Urination Defecation Physiologic Parameters

10. Body composition Body mass Lean body mass Body fat Total body water Percent body water Change in total body water per unit time Body mass Lean body mass Body fat Total body water Percent body water Change in total body water per unit time

11. Activity - normal Total number of steps Total distance traveled Amount of time in motion Amount of time climbing Average velocity Grooming Sleeping/Resting Exploratory novel stimuli Total number of steps Total distance traveled Amount of time in motion Amount of time climbing Average velocity Grooming Sleeping/Resting Exploratory novel stimuli

12. Activity - abnormal Circling Rolling Stumbling Scratching Death Circling Rolling Stumbling Scratching Death

13. Drinking Time spent at water lick Volume of water intake Frequency of water intake Time spent at water lick Volume of water intake Frequency of water intake

14. Eating Time spent eating Volume of food intake Frequency of food intake Food preference Time spent eating Volume of food intake Frequency of food intake Food preference

15. Urination Volume of urine production Urine specific gravity Frequency of micturation Volume of urine production Urine specific gravity Frequency of micturation

16. Defecation Volume of feces production Frequency of elimination Fecal water content Volume of feces production Frequency of elimination Fecal water content

17. Physiologic Parameters HR RR Temp Blood gases BP - systolic, diastolic, mean HR RR Temp Blood gases BP - systolic, diastolic, mean

18. Reproduction Breeding Nesting Parturition Lactation/nursing Breeding Nesting Parturition Lactation/nursing

19. Breeding Number of matings Mating time per mating Total mating time Completed breeding Number of matings Mating time per mating Total mating time Completed breeding

20. Nesting time producing a nest

21. Parturition Time in delivery Total animals per litter Total animals lost per litter Time in delivery Total animals per litter Total animals lost per litter

22. Lactation/nursing total nursing time nursing frequency total nursing time nursing frequency

23. Biosecurity Sentinel animals Serology DNA analysis Sentinel animals Serology DNA analysis