1. National Institute of Health Pathom Sawanpanyalert, MD, DrPH National Institute of Health Department of Medical Sciences Ministry of Public Health, Thailand

3. Roles of the National Institute of Health Serves as national reference laboratories for clinical diagnoses and epidemiological studies of infectious and non-infectious diseases Serves as national reference laboratories for clinical diagnoses and epidemiological studies of infectious and non-infectious diseases Conducts and co-ordinates research projects for prophylaxis and therapy of infectious and non-infectious diseases or syndromes of national importance and for public welfare Conducts and co-ordinates research projects for prophylaxis and therapy of infectious and non-infectious diseases or syndromes of national importance and for public welfare

4. Research facilities for infectious diseases Research facilities for infectious diseases Facilities and equipment: biosafety cabinets, autoclaves. CO2 incubators, microscopes (including scanning and transmission election microscopes), PCR machines, DNA sequencers, FACS machines, beta counters and biosafety level-3 containment laboratories for in vitro and in vivo experiments

5. Laboratory Tests Serological tests Serological tests Isolation and characterization Isolation and characterization PCR and other nucleic acid tests PCR and other nucleic acid tests Health profile tests Health profile tests Special laboratory tests Special laboratory tests Quality system complies with ISO 9001, ISO 15189 and ISO 17025 Quality system complies with ISO 9001, ISO 15189 and ISO 17025

6. Health Research Areas Infectious Diseases Infectious Diseases Non-infectious Diseases Non-infectious Diseases 1. Research for reference laboratory testing services 2. Research on public health problems 3. Research and development on diagnostic kits, drugs and vaccines

7. Infectious Diseases HIV-1 Subtype E Vaccine Development HIV-1 Subtype E Vaccine Development Collaborates with the National Institute of Infectious Diseases Collaborates with the National Institute of Infectious Diseases Antiretroviral Drug Resistance Surveillance Antiretroviral Drug Resistance Surveillance Collaborate with International Medical Center of Japan and NIID Collaborate with International Medical Center of Japan and NIID Diagnosis of Opportunistic Fungi Diagnosis of Opportunistic Fungi Collaborate with Chiba University Collaborate with Chiba University Emerging and Re-emerging Diseases Surveillance Emerging and Re-emerging Diseases Surveillance Collaborates with US CDC Collaborates with US CDC Tuberculosis Diagnosis Tuberculosis Diagnosis Collaborates with Colorado State University Collaborates with Colorado State University Antimicrobial Resistance Surveillance, supported by WHO Antimicrobial Resistance Surveillance, supported by WHO Influenza and Avian Influenza Vaccine Development Influenza and Avian Influenza Vaccine Development Leptospirosis Test Kit and Vaccine Development Leptospirosis Test Kit and Vaccine Development Dengue Haemorrhagic Fever Surveillance Dengue Haemorrhagic Fever Surveillance WHO Global Salmonella Surveillance WHO Global Salmonella Surveillance

8. Non-infectious Diseases National neonatal Screening Programme National neonatal Screening Programme Thalassemia Screening Thalassemia Screening Biomonitoring of Toxic Substances Biomonitoring of Toxic Substances

9. Major emerging and Remerging Diseases under the laboratory- based surveillance: 1. Acute Diarrhea 2. Acute Viral Hepatitis 3. Influenza 4. Fever or Fever with unknown origin 5. Meningococcal Meningitis 6. Encephalitis 7. Legionnaire ’ s Disease 8. Hand-Foot-Mouth Disease and Herpangina 9. Haemorrhagic Fever with Renal Syndrome

10. Roles in Thai NIH in Disaster Management: Tsunami (December 2004) 1. Laboratory-based surveillance of communicable diseases (post-Tsunami) 2. Assist in victim identification (DNA matching) 3. Provision of test kits for use in diagnosis and surveillance (post- Tsunami)