2. 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 100 200 300 400 500 Next round 100 200 300 400 500 Glorious glands Pathology Biotech Bonanza It’s in the Genes This & That Disease Detectives

3. Glorious glands100 hormone produced by pituitary gland often misused by athletes Ans: What is growth hormone? Return.

4. Glorious glands 200 Hormone produced by the islets of Langerhans Ans: What is insulin? Return.

5. Glorious glands 300 Hormones that are released during fight or flight response Ans: What are epinehrine/norepinephrine or adrenaline/noradrenaline ? Return.

6. Glorious glands 400 Too much growth hormone during childhood Ans: What giantism? Return.

7. Glorious glands 500 Hormone that controls internal clock Ans: What is melatonin? Return.

8. Pathology 100 Objective abnormalities Ans: What are signs? Return.

9. Pathology 200 Subjective abnormalities Ans: What are symptoms? Return.

10. Pathology 300 Cancer specialist Ans: What is an oncologist? Return.

11. Pathology400 Pattern of a disease’s development Ans: What is pathogenesis? Return.

12. Pathology 500 Seven warning signs of cancer Ans: What are sores that don’t heal, unusual bleeding, change in wart, lump, persistant cough, chronic indigestion, change in bowel function ? Return.

13. Biotech Bonanza100 “start” end of electrophoresis has this charge Ans: What is negative? Return.

14. Biotech Bonanza 200 The end of the gel where you find smallest pieces of DNA Ans: What is the positive end or “finish” line? Return.

15. Biotech Bonanza 300 Scissors used to cut DNA Ans: What are restriction enzymes? Return.

16. Biotech Bonanza 400 Small circular pieces of bacterial DNA Ans: What is a plasmid? Return.

17. Biotech Bonanza 500 The steps of genetically engineering a protein Ans: What are 1. isolating gene and plasmid, 2. restriction digest, 3. ligation, 4. transformation,5. fermentation, 6. harvesting (lysing) and 7.purification, ? Return.

18. It’s in the Genes 100 Protein product used to treat diabetes made by this gene Ans: What is insulin gene? Return.

19. It’s in the Genes 200 gene that promotes tumors Ans: What is an oncogene? Return.

20. It’s in the Genes 300 Technique to determine all of your entire genetic makeup Ans: What is genome sequencing? Return.

21. It’s in the Genes 400 Test to determine extra chromosomes during pregnancy Ans: What is aminocentesis and/or Chorionic Villi Sampling? Return.

22. It’s in the Genes 500 The reason that Valerie’s normal tissue had more bands in the DNA fingerprint compared to the tumor sample Ans: What 2 different alleles compared to 2 mutant alleles? Return.

23. This & That 100 Over secretion of a hormome Ans: What is hypersecretion? Return.

24. This & That 200 Under secretion of a hormone Ans: What is hyposecretion? Return.

25. This & That 300 Master gland Ans: What is the pituitary gland? Return.

26. This & That 400 How bpa affects the endocrine system Ans: What is acting as an endocrine disruptor, mimicking estrogen, possible link to diabetes? Return.

27. This & That 500 Hypothalamus sends more thyroid releasing hormome to pituitary which sends more thyroid stimulating hormone to thyroid which releases more thyroxine then hypothalamus sends less TRH…. Ans: What is a negative feedback loop? Return.

28. Disease detectives 100 5 Types of pathogenic organisms Ans: What are bacteria, viruses, protozoa, fungi, animals? Return.

29. Disease detectives 200 3 ways to get rid of pathogens Ans: What is disinfection, antisepsis, antibiotics, sterilization? Return.

30. Disease detectives 300 Epidemic that spans a large geographical area Ans: What is a pandemic? Return.

31. Disease detectives 400 3 Risk factors for acquiring disease Ans: What are age, genetics, lifestyle, environment, pre- existing conditon? Return.

32. Disease detectives 500 Difference between a tumor suppressor gene and an oncogene Ans: What is suppressor prevents cancer growth and oncogene promotes tumor growth? Return.

33. DAILY DOUBLE

34. Final Jeopardy Category: Biotechnology

35. A gene studied that has been linked to cancer (and its gene type) Ans: What is p53 and tumor suppressor gene?