1. 196019701980199020002010 Beyond 50 Years of Innovation

2. 196019701980199020002010 Beyond 1960: Our first facility is in the backyard of a house in Karlsruhe, Germany. The company produces magnets and power supplies. 1964: Fourier Transform (FT) research leads to significant increases in sensitivity. 1960: The first NMR, KIS, is created, operating at 25 MHz. Our Founders Professor Dr. Gunther Laukien Created first high-resolution systems for analytical chemistry. Recognized the power of nuclear magnetic resonance (NMR) and the need for impulse spectrometer. Established Bruker September 7, 1960. Dr. Emil Bruker - Co-Founder Professor Laukien was prevented from using his name commercially by academic agreement. Therefore, Dr. Bruker’s name was used when the company was formed.

3. 196019701980199020002010 Beyond 1974: IFS 110, Bruker’s first FT-IR spectrometer is introduced, launching a very successful product line. Late 1970s: Tomography systems for clinical and pre-clinical applications lead to whole-body clinical MRI instrumentation. Early 1970s: Sales offices are established throughout Europe, USSR, Australia and China. 1977: Bruker Meerestechnik established for small submersibles, oil exploration and tourism. 1970’s: First commercial 300 MHz NMR. 1970’s: First commercial 300 MHz NMR.

4. 196019701980199020002010 Beyond 1982: Bruker Spectrospin develops its first commercial FT-ICR: CMS-47. 1980: Bruker acquires Dr. Franzen Analysentechnik which adds quadruple mass spectrometers to the portfolio, including the MM1, the first mobile detection system. 1983: The first whole body MRI tomographs with air coil magnet reflect Bruker’s new focus on pre-clinical systems. 1988: Introduction of FT- Raman Product Line by Bruker Optics. 1988: Delivery of the first TOF-1, includes Neutral Desorption Ion Source followed by Multi-Photon Ionization MUPI. 1980’s: Development of first automated NMR systems with Autosamplers.

5. 196019701980199020002010 Beyond 1990: Bruker enters the ion mobility spectrometry market. 1993: Launch MultiProbe Ion Source for up to 10 samples on one target. 1994: First commercial ion trap system with electrospray source introduced. 1992: First REFLEX MALDI-TOF. 1994: Launch of SCOUT-26 Ion Source with X-Y movement stage. Early 1990’s: Development of CyroProbes for NMR.

6. 196019701980199020002010 Beyond 2000: Bruker begins a process of expansion. Bruker Daltonics and AXS combine in 2003 to a single corporation. By 2008, all Bruker units are combined, including Bruker Optics and Bruker Biospin, into a single public company ― Bruker Corporation. 2000: First shipment of the bench-top ion trap system, esquire3000. 2000: Bruker Daltonics IPO with NASDAQ listing. 2000: Launch of high throughput of autoflex MALDI-TOF.

7. 196019701980199020002010 Beyond

8. Bruker today. And beyond. Revenues in excess of US$ 1 billion. Dedicated to driving many more key innovations in the future. More than 4,000 highly motivated employees committed to progress and excellent customer relations. Think forward.