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Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis by Alexander Striebeck, David A. Robinson, Alexander.

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Presentation on theme: "Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis by Alexander Striebeck, David A. Robinson, Alexander."— Presentation transcript:

1 Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis by Alexander Striebeck, David A. Robinson, Alexander W. Schüttelkopf, and Daan M. F. van Aalten Open Biology Volume 3(9):130022 September 11, 2013 ©2013 by The Royal Society

2 Diagram of mannosylation pathways in the yeast Golgi. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society

3 Structure and conservation of Mnn9. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society

4 Active site of ScMnn9, RmMGS and ScKre2p/Mnt1p. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society

5 Activity assay of ScMnn9 wild-type and mutants. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society

6 Synergy of ScMnn9 and ScVan1. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society

7 Phenotypic analysis of native and complemented Saccharomyces cerevisiae ΔMNN9 strains. Alexander Striebeck et al. Open Biol. 2013;3:130022 ©2013 by The Royal Society


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