1. The Immune System memory and specificity Chapter 43 http://www.cellsalive.com/antibody.htm http://inet.uni2.dk/~iirrh/IIRhome.htm

2. Topics in Immunity Allergies : --plasma cells, immunoglobulins, and mast cells --antibodies and antigens HIV-AIDS -- infection of T cells -- place of T cells in the immune system distinguishing self from non-self

3. © Dennis Kunkel One of the culprits: ragweed pollen

4. Figure 42.14x Blood smear

5. Figures 42.15 & 16 Types and Differentiation of blood cells

6. Figure 43.8a,b The structure of a typical antibody molecule

7. Table 43.1 The Five Classes of Immunoglobulins

8. Figure 43.16 Effector mechanisms of humoral immunity

9. Figure 43.12 Clonal selection of B cells

10. Timing of primary and secondary immune response

11. pollen (the allergen) stimulates histamine release from mast cells

12. Figure 43.18 Mast cells, IgE, and the allergic response

13. Figure 43.14 An overview of the acquired immune responses 2

14. Topics in Immunity Allergies : --plasma cells, immunoglobulins, and mast cells --antibodies and antigens HIV-AIDS -- infection of T cells -- place of T cells in the immune system distinguishing self from non-self

15. Figure 42.14x Blood smear

16. Figures 42.15 & 16 Types and Differentiation of blood cells

17. Figure 43.9 The interaction of T cells with MHC molecules

18. Structure and positioning of the Major histo- compatibility complex (MHC) proteins Class IClass II

19. Interaction of an MHC protein with its antigen Class I

20. Cytotoxic T cell action (FIG. 43.16)

21. Clonal selection of Helper T cells and Cytotoxic T cells (FIG. 43.15)

22. Figure 43.14 An overview of the acquired immune responses 1

23. Figure 43.14 An overview of the acquired immune responses 2

25. Figure 43.14 An overview of the acquired immune responses 3

26. Presenting antigens: CD4 helps stabilize the connection. (usually a macrophage)

27. Figure 43.19 A T cell infected with HIV

28. Figure 43.19x1 HIV on a lymphocyte, detail

29. Figure 18.7 HIV, a retrovirus

30. Figure 43.19x2 HIV budding

31. Figure 43.20 The stages of HIV infection

32. Only cells with both CD4 proteins and chemokine receptor proteins (CXCR4, CCR5) are vulnerable to the HIV virus. These are the central cells in the immune system.

34. Figure 43.14 An overview of the acquired immune responses 3

35. Figure 43.14 Epitopes (antigenic determinants)

36. Topics in Immunity Allergies : --plasma cells, immunoglobulins, and mast cells --antibodies and antigens HIV-AIDS -- infection of T cells -- place of T cells in the immune system distinguishing self from non-self