1. Presented by Dr. Soe Sandi Tint
Effects of Oral Hypoglycemic Agents, Insulin And Life Style modifications On Glycemic control of Type 2 Diabetes Patients in Thailand
Presented by
Dr. Soe Sandi Tint

2. Background and Rationale
Diabetes Mellitus (DM) is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of Insulin
Type 2 Diabetes Mellitus is a Global Pandemic diseases
Chronic illness that requires continuing medical care, ongoing patient self-management education and support, life style modifications and regular monitoring of their blood glucose level within normal limit to prevent severe complications

3. Background and Rationale
Globally, about 346 million people are suffering Diabetes
Many glycemic uncontrolled Diabetes patients got complications after 5 years of being diagnosed as Diabetes
In Thailand 2006, only 26.3% of participants in Thai Diabetes Registry Project got control of HbA1c < 7%

4. Background and Rationale
Metformin (OHA) is the preferred initial pharmacological agent for type 2 Diabetes
Life style modification is also one of the way to achieve the target glycemic control level of HbA1c
Treatment with OHA, Insulin (pharmacological treatment) and Life style modifications (non-pharmacological treatment) is know to reduce glycemia in patients with type 2 Diabetes
In thailand, it is still unknown that which treatment attains target HbA1c level below 7%

5. Research Questions
What are the baseline characteristics (Gender, Age, BMI, Duration of Diabetes, Occupation, Health care financing) among type 2 Diabetes patients in Thailand?
What are the prevalence of complications among type 2 Diabetes patients in Thailand?
What are the prevalence of Glycemic control and uncontrolled level among type 2 Diabetes patients in Thailand?
What is the effective treatment between pharmacological (OHA, Insulin, both OHA and Insulin) and non-pharmacological among type 2 Diabetes patients in Thailand?
What is the association between Glycemic level (control and uncontrolled) and baseline characteristics among type 2 Diabetes patients in Thailand?

6. Research Hypothesis
There is association between Glycemic level (control and uncontrolled) and baseline characteristics among type 2 Diabetes patients in Thailand
Life style modifications (non-pharmacological treatment) and OHA (pharmacological treatment) are the best effective treatment to attain the target HbA1c level (< 7%)

7. Objectives
To describe the baseline characteristics (Gender, Age, BMI, Duration of Diabetes, Occupation, Health care financing) among type 2 Diabetes patients in Thailand
To describe the prevalence of complications among type 2 Diabetes patients in Thailand?
To describe the prevalence of Glycemic control and uncontrolled level among type 2 Diabetes patients in Thailand?
To assess the effects of pharmacological and non-pharmacological treatment on glycemic control among type 2 Diabetes patients in Thailand?

8. Significant of the study
In Thailand, there is not much information and studies about the effects of OHA, Insulin (pharmacological treatment) and Life style modifications (non-pharmacological treatment) on Glycemic control of Type 2 Diabetes patients

9. Research Methodology Study Design Cross sectional analytical study
Study Area
Ministry of Public Health and Bangkok metropolitan Administration Hospitals in Thailand
Study Population
Type 2 Diabetes patients aged between

10. Research Methodology Inclusion Criteria
Type 2 Diabetes alone patients who are on the treatment of OHA, Insulin, both OHA and Insulin (Pharmacological treatment) and life style modifications (Non-pharmacological treatment)
Sample Size
Sample = 8421 patients
Study Period

11. Research Methodology Sampling Technique
Samples were selected based on the probability proportional to sixe of the patients for each hospital

12. Research Methodology Data Analysis Process Descriptive Statistics
- Independent variables were described by using frequency and
percentage for categorical data and mean, standard deviation
were used for continuous data
- HbA1c < 7% as control group and >= 7% as uncrontrol group
were analyzed as dependent variables

13. Research Methodology Data Analysis Process Analytical statistics
- Bivariate analysis was done to measure the association between
dependent variable and independent variables
- Logistic regression was used in this analysis
- Multivariate analysis – variable having p value 0.25 or less was
included in the Multivariate model

14. Research Methodology Limitation of the study
Resource and time constrain
Insufficient data and missing values in the data (secondary data)

15. RESULTS

16. Descriptive Analysis

17. Descriptive Analysis

18. Analytical Statistics

19. Analytical Statistics

20. Thank You !