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2003-2004 GIHB Pharmacology Review 19 September 2015 3:29 AM.

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Presentation on theme: "2003-2004 GIHB Pharmacology Review 19 September 2015 3:29 AM."— Presentation transcript:

1 2003-2004 GIHB Pharmacology Review 19 September 2015 3:29 AM

2 Activated charcoal Antidote

3 Albendazole Antihelminthic Treatment of intestinal roundworms

4 Alosetron IBS treatment 5HT 3 receptor antagonist

5 Aluminum hydroxide Antiulcer Antacid

6 Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking

7 Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking

8 Anthraquinones cascara segrada, danthron, senna Contact cathartics

9 Aprepitant dimenhydrinate Antiemetic Neurokinin 1 receptor antagonist

10 Arsenicals Tropical antiparasitic Treatment of African Trypanosomiasis in CNS Melarsoprol

11 Atropine Anticholinergic Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning

12 Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

13 Balsalazide NSAID (salicylate) Treatment of IBD

14 Bisacodyl Contact cathartic

15 Bismuth subsalicylate Antiulcer Antidiarrheal

16 Budesonide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled OR treatment of IBD

17 Calcium carbonate Antiulcer Antacid

18 Cascara sagrada Contact cathartic Anthraquinone derivative

19 Castor Oil Contact cathartic

20 Cimetidine Antihistamine Antiulcer H 2 receptor antagonist

21 Cisapride Prokinetic agent 5HT 4 agonist

22 Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

23 Danthron Contact cathartic Anthraquinone derivative

24 Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Antiemetic Anti-inflammatory steroid Not by inhalation

25 Diethylcarbamazine Antihelminthic Treatment of intestinal and tissue roundworms

26 Dimenhydrinate Antihistamine Antiemetic H 1 receptor antagonist

27 Diphenhydramine Classical antihistamine Antiemetic H 1 antagonist

28 Diphenoxylate docusate Antidiarrheal Opiate

29 Docusates Lubricating laxatives Stool softeners

30 Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

31 Dronabinol Antiemetic Cannabinoid

32 Droperidol Antiemetic D 2 receptor antagonist

33 Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

34 Granisetron Antiemetic 5HT 3 receptor antagonist

35 Infliximab TNF inhibitor Anti-TNF monoclonal antibody Treatment of IBD

36 Iodoquinol Antiparasitic Treatment of protozoal infections

37 Ipecac Emetic

38 Ivermectin Antihelminthic Treatment of intestinal and tissue roundworms

39 Kaolin Antidiarrheal

40 Lactulose Saline (osmotic) cathartic

41 Lansoprazole Antiulcer H + /K + ATPase inhibitor

42 Loperamide Antidiarrheal Opiate

43 Magnesium hydroxide Antiulcer Saline (osmotic) cathartic Antacid

44 Mebendazole Antihelminthic Treatment of intestinal roundworms

45 Meclizine Antihistamine Antiemetic H 1 receptor antagonist

46 Meglumine antimonate Tropical antiparasitic Organic antimonial Treatment of Leishmaniasis

47 Melarsoprol Tropical antiparasitic Treatment of African Trypanosomiasis in CNS

48 Mesalamine (5-ASA) NSAID (salicylate) Treatment of IBD

49 Methylcellulose Bulk laxative

50 Metoclopramide Prokinetic agent Antiemetic D 2 antagonist

51 Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

52 Mineral oil Lubricating laxative Stool softener

53 Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

54 Misoprostol Prostaglandin Antiulcer

55 Nifurtimox Tropical antiparasitic Treatment of South American Trypanosomiasis; Chagas disease

56 Olsalazine NSAID (salicylate) Treatment of IBD

57 Omeprazole/esomeprazole Antiulcer H + /K + ATPase inhibitor

58 Ondansetron Antiemetic 5HT 3 receptor antagonist

59 Organic antimonials Tropical antiparasitic Treatment of Leishmaniasis sodium stibogluconate meglumine antimonate

60 Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

61 Pantoprazole Antiulcer H + /K + ATPase inhibitor

62 Paromomycin Antiparasitic Aminoglycoside antibiotic Treatment of protozoal infections

63 Pectin Antidiarrheal

64 Pentamidine Tropical antiparasitic Treatment of African Trypanosomiasis

65 Polyethylene glycol - electolyte solution Antidote Cathartic

66 Praziquantel Antihelminthic Treatment of trematode (fluke) and cestode (tapeworm) infections

67 Procarbazine Antineoplastic Miscellaneous Probably acts as alkylating agent

68 Prochlorperazine Antiemetic D 2 receptor antagonist Phenothiazine

69 Promethazine Classical antihistamine Antipsychotic Antiemetic H 1 antagonist

70 Pyrantel Pamoate Antihelminthic Treatment of intestinal roundworms

71 Pyrimethamine Antimalarial Protein and nucleic acid synthesis inhibitor Plasmodial dihydrofolate reductase inhibitor

72 Rabeprazole Antiulcer H + /K + ATPase inhibitor

73 Ranitidine Antihistamine Antiulcer H 2 receptor antagonist

74 Rebamipide Antiulcer

75 Senna Contact cathartic Anthraquinone derivative

76 Scopolamine Anticholinergic Antiemetic Muscarinic receptor antagonist

77 Simethicone Anti-flatulent

78 Sodium bicarbonate Antiulcer Antidote Antacid Alkalinization of urine to treat drug toxicity (esp. barbiturates, salicylates, methanol)

79 Sodium phosphate Saline (osmotic) cathartic

80 Sodium stibogluconate Tropical antiparasitic Organic antimonial Treatment of Leishmaniasis

81 Sucralfate Antiulcer

82 Sulfasalazine Disease modifying anti-rheumatic drug (DMARD) Metabolized to sulfonamide + salicylate (NSAID) Treatment of IBD

83 Suramin Tropical antiparasitic Treatment of African Trypanosomiasis

84 Tegaserod IBS treatment 5HT 4 receptor agonist

85 Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

86 Thiabendazole Antihelminthic Treatment of intestinal roundworms


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