1. Should you buy an e-textbook?

2. A Selective History of Physiological Psychology

3. You look at where you’re going and where you are and it never makes sense, but then you look back at where you’ve been and a pattern seems to emerge. R.M. Pirsig (1974) Zen and the Art of Motorcycle Maintenance

4. 4000-year-old trephinated skull trephines

5. Ancient Philosophers

6. Hippocrates ca. 460 B.C.-ca 370 B.C.

7. Aristotle 384 B.C. – 322 B.C.

8. Claude Galen 120-ca.216 A.D.

9. The Renaissance

10. Anatomy and Physiology

11. Leonardo da Vinci 1452-1519

12. 1489 1490 1506 a. drawing of brain; line intersections are center of sensory perception b. drawing of skull c. drawing of brain in skull, showing ventricles d. drawing of ventricles, based on wax mold made from ox brain

13. Andreas Vesalius 1514-1564

14. De Humani Corporis Fabrica

21. William Harvey 1578-1657

22. René Descartes 1596-1650

25. Albrecht von Haller 1708-1777

26. Localization of Function

27. Charles Bell 1774-1842 François Magendie 1783-1855

28. Johannes Peter Müller 1801-1858

29. Franz Joseph Gall 1758-1828

31. Paul Broca 1824-1880

34. Jean Pierre Flourens 1794-1867

35. Karl Lashley 1890-1958

37. Electrical Bases of Neural Activity

38. Luigi Galvani 1737-1798

39. Critical Experiment 1791

40. Alessandro Volta 1745-1827 Critical Experiment 1800

41. Emil du Bois-Reymond 1818-1896

42. Hermann L.F. von Helmholtz 1821-1894

43. Sir Charles Sherrington 1857-1952

45. Histology of the Nervous System

46. Marie Bichat 1771-1802

47. Camillo Golgi 1843-1926

50. Santiago Ramon y Cajal 1852-1934

54. Chemical Bases of Nervous Function

55. Claude Bernard 1813-1878

57. Sir Henry Dale 1875-1968

58. vagus nerve Ringer’s solution frog’s heart Dale’s Experiment 1. Stimulate the vagus nerve and the heart slows down 2. Add acetylcholine to the Ringer’s solution and the heart slows down

59. Otto Loewi 1873-1961

60. vagus nerve Ringer’s solution frog’s heart Loewe’s Experiment 1. Stimulate the vagus nerve and the heart in beaker A slows down THEN 2. Transfer Ringer’s solution from A to B and heart in B slows down A B transfer Ringer’s

61. Synaptic Plasticity

62. Donald Hebb 1904-1985

63. Hebb’s Postulate of Learning D.O. Hebb (1949) Organization of Behavior. N.Y.: Wiley & Sons, p. 62.