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Joost Hutsebaut, Kirsten Catthoor, and Dineke Feenstra

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1 Joost Hutsebaut, Kirsten Catthoor, and Dineke Feenstra
Assessment and treatment of severe personality disorders in adolescence ISSPD Congress 2007 The Hague, September 19 Joost Hutsebaut, Kirsten Catthoor, and Dineke Feenstra

2 What do you know about personality disorders in adolescence
What do you know about personality disorders in adolescence??? Let’s start with a little quiz…

3 Thesis 1 In DSM-IV-TR (2000), age is no criterion for the diagnosis of personality disorders. In other words, clinicians are allowed to give a diagnosis of PD to a minus 18-years old.

4 Multiple choice 1 A. True in all cases
B. True in all cases except for the diagnosis of antisocial PD C. Only true for the borderline PD D. Not true

5 Answer 1 The correct answer is B. DSM-IV-TR p. 687
There is no age criterion for the diagnosis of PD in DSM-IV-TR, except for the antisocial PD.

6 Thesis 2 The prevalence of borderline PD in adults and adolescents is about the same.

7 Multiple choice 2 A. Not true, the prevalence of borderline PD is higher in adults. B. Not true, the prevalence of borderline PD is higher in adolescents. C. True D. There is no information on this.

8 Answer 2 The correct answer is C.
There is empirical evidence that the prevalence of borderline PD is (more or less) the same in adults and adolescents in as well a community as a clinical sample. 14.4% of ‘community’ adolescents can be diagnosed with a PD.

9 Thesis 3 The diagnosis of BPD in adolescence predicts more axis 1 and axis 2 disorders in early adulthood.

10 Multiple choice 3 A. True. B. Only true for axis 1, not for axis 2.
C. Only true for axis 2, not for axis 1. D. Not true.

11 Answer 3 The correct answer is A: the diagnosis of PD in adolescence predicts as well axis 1 as axis 2 disorders in early adulthood. Axis 1 disorders are a highly sensitive marker for the seriousness of the PD.

12 Thesis 4 What is the most specific feature of a borderline PD in adolescence?

13 Multiple choice 4 A. Impulsivity. B. Instability of affect.
C. Identity confusion. D. Suicidal ideation and gestures.

14 Answer 4 The correct answer is B.
The most typical feature of borderline PD in adolescents is instability of affect, in adults it is impulsivity.

15 Thesis 5 4 to 20% of adult patients in an inpatient setting self mutilates. What is the percentage of self injurious behavior in adolescents in an inpatient treatment setting?

16 Multiple choice 5 A. Less than adults, 5 to 10%.
B. The same as adults, 10 to 20%. C. A little more than adults, 25-40%. D. Much more than adults, 40-60%.

17 Answer 5 The correct answer is D.
90% of all self injurious behavior happens in adolescence.

18 (Because of privacy reasons this information has been omitted)
Case Study (Because of privacy reasons this information has been omitted)

19 Psychotherapy in PD adolescents?
Review of 25 empirically supported psychotherapies in adolescents (Weisz and Hawley, 2002) 14 effective 7 ‘adult’ models, 6 ‘child’ models 1 ‘adolescent’ model Review of 34 studies of CBT in adolescents (Holmbeck et al., 2003) 9 (26%) involved developmental issues 1 studied a developmental factor as moderator of outcome PD in adolescence? No RCT’s No age-specific treatment guidelines Few treatment manuals (Bleiberg, 2001), Miller et al (2007), Freeman and Reinecke (2007)

20 Psychotherapy in PD adolescents?
Conclusion No evidence based adolescence-oriented psychotherapy models for PD Almost no well developed treatment manuals No age-specific practice guidelines (APA etc) Challenging!

21 What are our objectives today?
Proposal of practice guidelines for the assessment and treatment of severe PD in adolescents (mainly cluster B) Pragmatically: how to design a concrete treatment trajectory Systematically: from intake to follow-up Not restricted to one theoretical frame Based on: Literature and evidence based results of research on PD in adults Available literature on (treatment of) PD in adolescence Literature on developmental psycho(patho)logy in adolescence Our clinical experiences with PD adolescents

22 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

23 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

24 Empirical research on PD in adolescence
Is it allowed to give a diagnosis of PD to an adolescent? Is it wise to give a diagnosis of PD to an adolescent? How often do PD occur in adolescence? How do PD develop throughout adolescence?

25 Is it allowed to give a diagnosis of PD to an adolescent?
DSM‑IV‑TR (APA, 2000, p. 687): PD can be diagnosed in adolescents Clinicians should be careful Symptoms have to be present during 1 year Exception: antisocial PD should not be diagnosed before the age of 18 yrs How well is this known in the field???

26 Is it wise to give a diagnosis of PD to an adolescent?
This is also an empirical issue Can PD be diagnosed in a reliable way in adolescence? Is it a valid diagnosis? Diagnosis refers to the same characteristics Diagnosis correlates with similar associated problems Diagnosis predicts similar problems in the future Diagnosis has some stability over time

27 Is it wise to give a diagnosis of PD to an adolescent? 1. Reliability
There are as many PD adolescents as PD adults in a clinical sample (Westen, Shedler et al., 2003; Grilo, McGlashan et al., 1998) and in a community sample (Johnson, Cohen et al., 2000). Almost all specific PD occur in the same frequency Exception: antisocial and avoidant PD These PD adolescents show a similar pattern of co-morbidity 2/3 between 2 and 9 PD diagnoses in a clinical sample 50% 2 or more in a community sample

28 Is it wise to give a diagnosis of PD to an adolescent. 2
Is it wise to give a diagnosis of PD to an adolescent? 2. Construct validity EFA on all PD symptoms gives evidence for 10 empirically derived factors, similar to DSM IV PD categories (Durrett & Westen, 2005) Q analysis based on clinical descriptions gives evidence for similar categories of PD in adults and adolescents (Westen, Shedler et al., 2003) EFA on personality symptoms (DIPSI, SIPP) has a similar structure in adolescents as in adults (De Clercq et al., 2006; Feenstra et al., 2007)  Personality pathology in adolescence has a similar structure as personality pathology in adults

29 PD diagnosis in adolescence is associated with:
Is it wise to give a diagnosis of PD to an adolescent? 3. Concurrent validity PD diagnosis in adolescence is associated with: More suicidal ideation and acts (Westen et al., 2003; Braun- Scharm, 1996) More problems at school and less friends (Westen en al., 2003) More behavioral problems and problems at school (Johnson et al., 2005) Alcohol abuse, smoking and illegal drug abuse (Serman et al., 2002) More sexual partners and high risk sexual contacts (Lavan & Johnson, 2002) More violent acts (assault, burglary, initiating fights, threatening) More MH service use, more medication use (Kasen et al., 2007)

30 Is it wise to give a diagnosis of PD to an adolescent. 4
Is it wise to give a diagnosis of PD to an adolescent? 4. Predictive validity PD diagnosis in adolescence predicts: Subsequent failure in school (Johnson et al., 2005) More negative affects, distress, problems in social support, living, mobility, finances and health in adulthood (Chen et al., 2006) More health problems, more problematic social contacts, less psychological wellbeing and more adversities in early adulthood (Chen et al., 2006) More conflicts with family members in early adulthood (Johnson et al., 2004) More depression in early adulthood (Daley et al., 1999) More interpersonal stress in early adulthood (Daley et al., 2006) More relational dysfunctioning in romantic relations (Daley et al., 2000) More anxiety, mood and substance abuse disorders in early adulthood (Johnson et al., 1999) More illegal dugs abuse and crisis intervention (Levy et al., 1999)

31 Is it wise to give a diagnosis of PD to an adolescent? Differences
Internal consistency of PD criteria of a given PD is generally lower in adolescence than in adulthood (except for BPD and dependent PD) (Becker et al., 2001) The overlap of criteria from different PDs is larger, suggesting a more diffuse range of psychopathology (Becker et al., 1999) There is evidence for more co-morbidity between different (A, B, C) clusters (Becker et al., 2000)

32 BPD in adolescence Frequency of BPD and BPD traits is similar in adolescent and adult clinical sample (Becker et al., 2002) Symptoms and phenomenology of BPD is similar for adolescent girls and adults (Bradley et al., 2005) Internal consistency of BPD criteria in adolescence is high (.76) (Becker et al., 1999) Q analysis gives evidence for similar subgroups of BPD girls as in adults (Bradley et al., 2005)

33 BPD in adolescents: Types and associated axis 1 disorders
Different types of BPD (Bradley et al., 2005) High functioning and internalizing Histrionic Depressive internalizing Angry and externalizing  case study Associated axis 1 disorders (Becker, 2006) Suicidal gestures and emptiness (depressive disorders and alcohol abuse disorders) Affective instability, uncontrolled anger and identity disturbance (anxiety disorder and conduct disorder) Unstable relationships and fear of abandonment (anxiety disorder) Impulsivity and identity disturbance (conduct disorder and substance abuse disorder)

34 BPD in adolescence: some differences
Individual BPD criteria have a higher general positive predictive power than in adults (1 symptom generally predicts better the overall disorder) Fear of abandonment is the best inclusion criterion in adolescence (if present, high predictive power for BPD) Uncontrolled anger is for adolescents the best exclusion criterion, for adults impulsivity (if absent, no BPD) Taken together is affective instability for adolescents and impulsivity for adults the most useful criterion.

35 Prevalence of PD in adolescence
PD 14,4% (CIC study) Cluster A 5,9% Paranoid 3,3% Schizoid 1,1% Schizotypal 1,7% Cluster B 7,1% Borderline 2,4% Histrionic 2,5% Narcissistic 3,1% Cluster C 4,9% Avoidant 2,0% Dependent 2,2% Obsessive-compulsive 1,1%

36 Course of PD in adolescence
CIC-study PD traits decrease with 28% between adolescence and early adulthood (Johnson et al., 2000) Stability is lowest between 14 and 16 yrs (Johnson et al., 2000) Clinical samples Modest stability for dimensional measures of personality pathology (Daley et al., 1999; Grilo et al., 2001) After two yrs: 74% diagnosis PD (83% girls, 56% boys); stability of specific PD is low (Chanen et al., 2004) Stability is high for schizoid and antisocial PD; modest for borderline, histrionic and schizotypal PD and low for other Pds (Chanen et al., 2004)

37 Is it wise to give a diagnosis of PD to an adolescent
Is it wise to give a diagnosis of PD to an adolescent? General conclusions The diagnosis of PD can be made in a reliable way in adolescence About 10-15% of adolescents have a PD The diagnosis of PD in adolescence has excellent concurrent validity: it is associated with many parameters of distress and dysfunctioning. The diagnosis of PD has modest predictive validity. It reliably predicts dysfunctioning in the future, but the diagnostic stability of specific PD categories is rather small. Diagnostic stability of the general PD diagnosis on the other hand is good. As in adults, co-morbidity is high, but probably broader (encompassing aspects of other PD clusters). BPD in adolescents has got excellent internal consistency, construct validity and concurrent validity. There is evidence that the weaker stability of BPD can be ascribed mainly to the instability of the affective and impulsive symptoms.

38 How to conceive personality disorders?
PD is a chronic condition of structural vulnerability, that develops from early childhood through adolescence into adulthood and that expresses itself in interaction with a changing environment in a fluctuating pattern of maladaption. Chronic condition, but fluctuating expression Expression depends on context Expression might depend on developmental factors Different developmental pathways, starting from childhood

39 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

40 Assessment General remarks
Use of multiple informants (parents, teachers, children) Attitude of the clinician Assessment should be evidence based Aim not only diagnostic assessment, but also to increase the motivation of the patient

41 Assessment Developmental history
Indicators of high risk for the development of personality disorders

42 Assessment Intelligence
Importance of intelligence testing Case: Kaufman Adolescent and Adult Intelligence Test (KAIT) Total - Crystallized Definitions Aud. Compreh. Double mean. 110 (75) 12 11 Fluid Rebus learning Logical steps Mystery codes 92 (30) 8 10

43 Assessment Neuropsychological testing
Gives additional information to validate the diagnosis of a PD Indicates the impact of a PD

44 Assessment Symptoms Case: Brief Symptom Inventory (BSI) Scale
Description Score Norm patients Norm population SOM Somatization 0.429 Below average Above average O-C Obsessive-Compulsive 1.667 High I-S Interpersonal Sensivity 1.25 Average DEP Depression 2.0 Very high ANX Anxiety 2.333 HOS Hostility 2.8 PHOB Phobic Anxiety 0.8 PAR Paranoid Ideation 2.4 PSY Psychoticism 1.8 GSI Global Severity Index 1.717 PST Positive Symptom Total 34.0 PSDI Positive Symptom Distress Index 2.676

45 Assessment Symptoms Case: Child Behaviour Checklist (CBCL)

46 Assessment Axis I Case: Anxiety Disorders Interview Schedule for DSM-IV, Child Version (Adis-C), Complemented with modules from the Structured Clinical Interview for DSM-IV axis I disorders (SCID-I) Diagnosis axis I: Posttraumatic stress disorder Substance dependence Conduct disorder

47 Assessment Axis II Case: Structured Clinical Interview for DSM-IV axis II Personality Disorders (SCID-II) Diagnosis axis II: Borderline Personality Disorder Frantic efforts to avoid real or imagined abandonment A pattern of unstable and intense interpersonal relationships characterized by alternating between extremes of idealization and devaluation Identity disturbance Impulsivity Recurrent suicidal behavior, gestures or threats, or self-mutilating behavior Affective instability Chronic feelings of emptiness Inappropriate, intense anger or difficulty controlling anger Transient, stress-related paranoid ideation or severe dissociative symptoms

48 Assessment Specific borderline characteristics
Suicide Risk Assessment Assessment of dissociation Case: Diagnostic Interview for Borderlines (DIB-R), included in Clinical Interview

49 Assessment Structural characteristics
Case: Questionnaires NEO-PI-R

50 Assessment Structural characteristics
Case: Projective tests (Rorschach)

51 Assessment Competence
Case: Competentie Belevingsschaal voor Adolescenten (CBSA), derived from the Self-Perception Profile for Adolescents (SPPA) Sv Sa Sp Fv Gh Hv Ge Scale scores 17 18 6 19 8 15 Percentile 95 82 4 97 3 16 48

52 Assessment Family Case: Family Assessment Device (FAD) Scale
Stepmother Patient Father Problem solving 2,667 3,000 3,167 Communication 2,556 Role fulfillment 2,636 2,273 2,272 Affective respons 2,833 Affective involvement 2,714 2,429 3,429 Family culture Global functioning 3,083 2,917

53 Assessment Conclusions case
Patient is diagnosed with a BPD on axis 2 and an associated PTSD, conduct disorder and substance dependence on axis 1. Underlying we see a low-level borderline organization: identity is fragmented, object representation are split, reality testing is fragile, defenses are immature. Nevertheless, we also see some adaptive coping mechanisms and a good self-reflexive capacity during the assessment. Because of her traumatically developed attachment, patient is unable to experience any form of ‘ safe’ intimacy or nearness. When stress increases (e.g. in case of approaching separation) patient loses the capacity to reflect and her adaptive coping mechanisms. She then turns to maladaptive coping mechanisms, like splitting, and aggressive and anti-social behavior to restore the lost balance. This antisocial behavior has to be understood as a way to protect her autonomy and her ‘self’ against unbearable feelings provoked by intimacy and related fear for abandonment.

54 From assessment to indication: levels of treatment setting
Outpatient treatment Partial hospitalization Brief inpatient hospitalization Extended inpatient hospitalization

55 Indication for treatment setting: Considerations about case study
Based on APA guidelines: extended inpatient treatment Persistent risk behavior Severe symptoms interfering with family and school life Risk of assaultive behavior towards others Co-morbid substance abuse Based on extra adolescent considerations (Bleiberg, 2001): extended inpatient treatment Insufficient resources to provide a safe environment at home Need for more structure and support Based on clinical experience There is a serious pitfall that she cannot deal with the pressure for attachment in an inpatient setting (psychological testing)

56 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

57 Designing a flexible treatment trajectory
Treatment should be seen as a continuous trajectory During different years (2-5 years) With changing intensity Stepped up and down: Preparation phase focused at psycho-education and motivation, crisis management and context regulation A residential phase to decrease stress at home and start a therapeutic process A day treatment phase to strengthen the achievements and anchoring them in real life A follow-up of booster sessions to support the internalized therapeutic process Involving psychotherapy, system therapy and pharmacotherapy

58 Designing a flexible treatment trajectory

59 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

60 Preparation phase: goals
Psycho education Context regulation Crisis management plan

61 Preparation phase: methods for psycho-education
Psycho-education is a necessary part of the treatment of PD (APA guidelines) Explanation about the symptoms, the origin and the course of the disorder, and the possibilities of treatment. Giving hope. It is not about ‘learning to live with the disorder’, but about ‘curing’. For patients and their family there’s often relief that the problems have a name, so they can start to understand them. Psycho-education helps to bring order in the chaos

62 Preparation phase: methods for psycho-education
Practical tips: Try to use the language adolescents are familiar with. Words like ‘psychiatric illness’ can be frightening. Mind the intelligence and cognitive skills of the adolescent and the parents and adapt your explanation to their limitations It might be necessary to dose the information and plan different sessions

63 Preparation phase: methods for psycho-education
Examples of standardized sentences for explaining the diagnosis: You came here because you have problems for quite a while and treatment didn’t help you enough so far. We’ve had several sessions with you and your parents and asked you to participate in some psychological testing. We think it’s important to find out what is really going on, in order to suggest a treatment designed for the problems you have

64 Preparation phase: methods for psycho-education
Your problems can be understood as making part of a (borderline) personality disorder. Easily speaking, it means that you have difficulties in dealing with your self, with your feelings, thoughts and behavior, and difficulties in contacts with other people. A borderline PD consists of 9 characteristics, 5 is enough for the diagnosis. This means that every patient with a borderline PD is different from every other patient. We now want to give you some information about the characteristics. Do you agree with that?

65 Preparation phase: methods for psycho-education
Fear of abandonment: You are afraid that people will drop you. You are convinced that people don’t care for you and that you’re worth nothing. You will do everything to avoid people leaving you, for example sending text messages all the time, insisting on your contacts on MSN People get irritated, feeling of being suffocated en they will try to avoid your claim So what happens is just that scenario where you are so afraight of

66 Preparation phase: methods for psycho-education
Affect instability: You feel like your affect is never stable, you can never be happy for some longer time Sometimes you feel so depressed en sad that suicide is all you can think of, and 1 minute later you are euphoric en busy You are easily irritated and your parents have the feeling they have to tread on eggs when you’re at home

67 Preparation phase: methods for psycho-education
From the psychological testing we learned that you have a splitted inner world, with anger and emptiness as the only possible ways of expressing your feelings. This means that your emotions are not easily accessible, and it is very difficult for you to differentiate what you really feel and experience. You don’t have tools to make your inner feelings more comprehensible for yourself.

68 Preparation phase: methods for psycho-education
You are very frightened, and you can only control that feeling by showing aggression. It is very difficult for you to make a difference between experiences in reality, and what you feel inside. F.e. when your therapist sets limits, when you are thinking of the humiliations of your stepfather, you will not always be able to make a distinction between these 2 situations. You will confuse your inner and outer world.

69 Preparation phase: methods for psycho-education
Because you are impulsive, as well in changing schools, living with your parents, using drugs and alcohol, as having sex with boys, there is a chance that you will be impulsive in terminating the treatment also. It will be important to focus on that when it’s difficult for you to fully cooperate.

70 Preparation phase: methods for psycho-education
You find it very difficult when people want to make close contact with you. You do not trust intimate relationships. You prefer to break contact yourself, to avoid that people will leave you. Therefore it will be extremely important to keep that pattern in mind in the relationship with your therapists.

71 Preparation phase: goals
Psycho-education Context regulation Crisis management plan

72 Preparation phase: methods for context regulation
What should be arranged for the treatment to be able to start? Financially Juridical Mobility (transport to treatment setting) Structured daily activity (in case of outpatient) Safe weekend destination (in case of inpatient)

73 Preparation phase: methods for context regulation
How can continuity before, during and after treatment be improved? Contact with referring psychiatrist/psychologist Contact with school Home visit by social worker Social network, neighborhood etc Use a clear therapeutic frame What rules about drugs and alcohol? Give an information sheet with basis rules, expectancies, treatment methods

74 Preparation phase: goals
Psycho-education Context regulation Crisis management plan

75 Preparation phase: methods for crisis management
Severe PD lead almost by definition to crises during treatment. Crises give agitation and can interfere with countertransference, leading to splitting in a team. Designing a plan for crisis management gives control and predictability The goal is to stabilize the crisis so the treatment process is not jeopardized Make clear agreements with patient and parents in advance, specifically about the availability of therapists Give clear roles to staff members in dealing with the crisis: medical care, psychological care, decision about transfer to other setting Agree with patient and parents on a plan for crisis management during the weekend or evening. Put it on paper.

76 Structure of the workshop
Assessment of PD in adolescence Empirical research on PD in adolescence Assessment of PD in adolescence and indication for treatment setting Designing a flexible treatment trajectory Preparation phase Integrative, adolescence-specific, treatment, including psychotherapy, system therapy and pharmacotherapy Relapse prevention and follow-up

77 Designing a flexible treatment trajectory

78 Designing an integrative, adolescence-specific treatment
Psychotherapy is treatment of first choice Dialectical Behavior Therapy Mentalization Based Treatment (Schema Focused Therapy) Pharmacotherapy should be considered as an ‘enabler’ of psychotherapy System therapy is a necessary complement of psychotherapy in adolescence

79 Some general remarks about psychotherapy for severe PD
Two evidence based models for treating BPD in adults (Cochrane review, 2006) Dialectical Behavior Therapy (Linehan, 1991) Mentalization Based Treatment (Bateman & Fonagy, 1999, 2004, 2006)

80 Dialectical Behavior Therapy
Based on cognitive-behavioural therapy Hierarchy of interventions: Interventions aimed at reducing self-mutilating behaviour Interventions aimed at behaviour that interferes with the therapeutic process Interventions aimed at improving quality of life Out-patient individual therapy, once a week, in combination with group therapy Empirical evidence for effectiveness of DBT (Koons, 2001; Linehan 1991, 1999, 2002; Turner, 2000; van den Bosch, 2002) Adaptations made for adolescents!

81 DBT in adolescence Adaptations (Miller et al., 2007)
Parents participate in the skill groups (multifamily skill training group) Shorter treatment Simpler hand-outs Simpler diary Including family therapy (as-needed base) Including extra skills that are relevant for parents or siblings Telephone consultations for parents A new module: walking the middle path, introducing three new dialectical dilemma’s

82 Mentalization Based Treatment
Psychodynamic oriented treatment program Attachment theory Primary aim: to enhance mentalization Outpatient treatment program (18 months) Empirical evidence for effectiveness of MBT (Bateman, 1999)

83 Some general remarks about pharmacotherapy for severe PD
Psychotherapy is treatment of first choice Pharmacotherapy as “enabler”, to make psychotherapy “more possible” No evidence based treatment methods Guidelines for adults, warnings for children and adolescents Controversies, for instance about SSRi’s

84 Some general remarks about pharmacotherapy for severe PD
Be aware of the differences in pharmacokinetics in children and adolescents: Percentage of body fat Lipophile binding Speed of metabolism Plasma proteins Demolition

85 Some general remarks about pharmacotherapy for severe PD
Symptom-targeted pharmacotherapy in patients with PD is confusing. Is the symptom (f.e. negative affect) part of the personality disorder, or is it part of an axis-1 disorder (f.e. major depressive disorder) Cochrane review: no exclusion of axis 1 disorders, except for psychotic disorders

86 Some general remarks about pharmacotherapy for severe PD
APA-guidelines (2001): 3 algorithms: Affective dysregulation Impulsive behavior Cognitive-perceptual symptoms No clinical trials More practice based than evidence based

87 Pharmacotherapy: some case study interventions
Because of the seriousness of the symptoms of our patient we choose a combinations of different products: Escitalopram 10 mg for heavy mood changes Quetiapine 300 mg for cognitive-perceptual symptoms, psychotic-like fears and impulsivity Topiramate 50 mg for dissociation, the images of sexual abuse and humiliations of step father Diazepam 5 mg for the side effects after alcohol stop.

88 Some general remarks about system therapy for severe PD
Is a necessary part of the treatment of a PD adolescent, on practice based arguments Youngsters can only change and grow within the context of their family. When there is no continuity between the therapy and the milieu at home, changes will not last long. Several different models have proven their solidity, but there is no evidence based background. New research can support the guideline of always working with the family of the adolescent.

89 Some general remarks about system therapy for severe PD
I-BAFT: integrative borderline adolescent family therapy Multidimensional family therapy, based on attachment theory Integrative family therapy with genograms and core qualities

90 How to design a flexible and effective treatment integrating those components?
Therapeutic relationship including limit setting How does developmental phase affect therapy for severe PD’s? What are goals and methods in different phases of the therapeutic process?

91 Therapeutic relation Install a therapeutic alliance based on cooperation Be transparent (about interventions, treatment goals etc) Avoid an expert or moralizing position. Balance between acceptance/validation and change/empathic confrontation

92 Therapeutic relation: limit setting
It is probably impossible to avoid setting limits (and it is probably damaging) There are three principles to keep in mind: Adolescents should be given a proper (and growing) responsibility Limits should not be administered in an automatic, procedural way, but with the mind of the adolescent in mind Therapists should be transparent about the ‘why’ of limit setting Be aware of extremes: authoritarian control versus excessive leniency (Miller et al., 2007)

93 How does developmental phase affect therapy for severe PD’s?
Methods and interventions Cognitive, emotional, social and identity development determine how to do therapy Attune to cognitive level, … Content/issues Developmental tasks determine what therapy is about (treatment goals) Sexual identity, separation from parents, …

94 Developmental guidelines for choosing methods and interventions
Based on cognitive development Be concrete (especially with adolescents under 15 yrs) Visualize Be careful with metaphors Don’t lean too much on hypothetical thinking Support critical thinking Practice meta-thinking

95 Developmental guidelines for choosing methods and interventions
Based on emotional development Be aware that affective instability is the core of BPD in adolescents Start by identifying ‘simple’ emotions before proceeding to complex mental states Give words to identify emotions Learn to discriminate between intensities and sorts of emotions Reinforce proper expression of emotions

96 Developmental guidelines for choosing methods and interventions
Based on social development Let the adolescent ‘save face’ Be aware of the enhanced vulnerability in groups Be aware that the attachment to peers might be as important (or even more) than the attachment to therapists Invest in installing a positive, accepting group norm

97 Developmental guidelines for choosing methods and interventions
Based on identity development Support autonomy What do you want to change? How do you want to use this session? Offer opportunities to separate Support critical thinking Give privacy Tolerate experimenting behavior

98 Developmental guidelines for determining treatment goals
Based on developmental tasks (12-15 yrs) Dealing with physical changes Constructing own frame of reference (norms, values) Connect with peers Based on developmental tasks (15-20 yrs) Becoming more independent from feedback of peers and adults Developing a stronger self-esteem Developing social and professional skills Re-constructing a relationship with parents

99 Goals and methods in different phases of the therapeutic process
Start phase Middle phase End phase

100 Start phase: Goals Install a secure, predictable environment
Enhance motivation / commitment Agree upon prior treatment goals Start by improving a sense of competence in the adolescent and his/her family Medication

101 Start phase: some methodological issues
About motivation ‘Roll with resistance’ Do not convince from an expert position Let the adolescent motivate himself by eliciting self-motivating expressions Use authentic and focused reinforcements to highlight advances How was it for you to experience you succeeded in managing stress in this way?

102 Start phase: some methodological issues
About improving competence Start by thinking about or even teaching skills to cope with stress Assist caregivers in achieving skills to remain in control even when facing internal and interpersonal turmoil Psycho-education Skill group

103 Start phase: some case study interventions
We predicted upcoming relational patterns If you tell me you always tend to break up friendships after some months, this might be happening here too. We looked for agreement on prior symptoms She was frightened by her cutting and burning, being afraid she would lose control About trauma: I understand this is something extremely important for you, which we will have to work on further in treatment, but at this moment I notice that talking about it gives you a lot of tension and often leads to cutting yourself.

104 Start phase: some case study interventions
We looked for alternatives to cope with stress We made a concrete ‘minute-to-minute’ crisis plan There was a joined consult with the therapist and psychiatrist about medication The family was taught some basic skills to prevent discussions from escalating

105 Middle phase: Goals Help the adolescent to relate symptoms to mental states that occur in the context of relations Help the adolescent to face developmental tasks, including developing a new relationship with parents

106 Middle phase: some methodological issues
About developing a reflective stance Identify and validate actual or recent mental states Differentiate and contextualize Internalize and help to take responsibility Digest and help to tolerate ambivalence Integrate in alternative behavior and mental states

107 Middle phase: some case study interventions
Tania often started therapy announcing how ‘crap’ she felt What do you mean by ‘crap’? How sad, angry, anxious? Can you remember when you noticed some change in how you felt? Attitude: it might be worth to explore in detail how you came to feel this way Can you understand why this (trigger) made you feel this way? How is it to understand yourself in this way?

108 Middle phase: some case study interventions
After three months, acting out dramatically increased (drinking, crossing limits) She wanted to stop treatment because it got ‘boring’ Can you help me to understand how it got this far? Where did you notice a change in motivation? This enhanced reflective stance made her aware of her fear for intimacy of group members I cannot tolerate it anymore. I don’t want to experience a goodbye of group members anymore She experienced extremely aggressive thoughts including group members, which made her angry With this broadening perspective, she was invited to rethink her decision to stop. We accepted her decision.

109 End phase: Goals Anticipate on reintegration
Prepare for loss associated with leaving Relapse prevention

110 End phase: some methodological issues
About relapse prevention Identify ‘traps’ Identify future life stressors Identify successful coping and new competencies Make a written therapy summary with your patient

111 Follow-up Stepped down care: gradually less intensive treatment and more intensive reintegration in school, work etc Booster sessions

112 Contact Email: joost.hutsebaut@deviersprong.nl
Website:


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