1. Günther Hiss August, 2006 Laboratory Automation an Overview

2. Requested Functionality Sample/User Management Instrument Control Data accessibility for your customers Data archiving etc…

3. Main Features + General data management + Laboratory Management + Automatic preparation and instrument control + Sample Workflow + External Data Access + Flexibility for customization ________________________ =

4. NMR Lab Organization with SampleTrack Company Data System Sample Management Web Interface Electronic Journal TM B-A C S S A M P L E C H A N G E R - T E C A N® P R E P A R A T I O N R O B O T - S A M P L E R A I L – G I L S O N ® R O B O T – B R U K E R B E S T User Management Analysis / Data Interpretation GC, LC Laboratories MicroTOF Esquire FT-MS

5. Sample Workflow through the Lab Sample Setup (define workflow for sample) Sample Verification (start of the workflow) Preparation (automatic or manual) NMR-Messurement(s) Approving the results Data archiving

6. Sample Registration through Spreadsheets EasyWeb EasyDialog Existing Company Data System Homemade Sample Order Setup – Serveral Possibilities

7. Robot with BRUKER BEST or other Methods Preparation and NMR Preparation Robot with / NMR or other Methods Manual prep + B-ACS

8. Barcode Identification for Vials and tubes Barcode Collar during NMR Measure- ment Submitted Vials

9. Barcode Identification for Racks and Wellplates Barcode Identification for Gilson Autosampler First Line: Sample Identifier Second Line: Geometry Identifier

10. Manual Preparation - OpenAccess For Open Access and Preparation Workplace CCD Handscanner

11. Scenario - Open Access Sample Registration with SampleTrack EasyDialog

12. Scenario - Full Integration with EasyWeb Order Setup with EasyWeb Laboratory Preparation MS Archive System

13. Scenario - Full Automation with SampleRail Company LIMS Laboratory Preparation

14. SampleTrack Software Components SampleTrack Client The User Interface for all accesses SampleTrack Communicator Responsable for all communication between the systems Easy Dialog customizable tool for sample setup SampleTrack Web Client/EasyWeb

15. SampleTrack Client – Status information

16. SampleTrack Web Client

17. A familiar user friendly environment with the EasyWeb tool for easy order setup EasyWeb

18. Other Applications Data Mining Search Engine -Experiment Parameters -Sample Information (Project Number/Journal Number) Web Interface Web Interface Visualization / Evaluation ® Calling application programs with the link to the data

19. Loading Data with and ®

20. Structure and spectra viewing including zooming in and out EMF files created by Internet Structure and Spectra Viewer

21. Web Search A simple and extended search tool

22. ORACLE DB TM Order Setup Laboratory Preparation TOPSPIN Data Interpretation Existing Company LIMS User Management Archive System B A C S S A M P L E C H A N G E R - T E C A N P R E P A R A T I O N R O B O T - S A M P L E R A I L – G I L S O N R O B O T – B R U K E R B E S T Topology

23. Automatic Sample Preparation and Sample Transfer with TECAN Evo and Bruker SampleRail…

24. Bruker SampleRail / Tecan Evo Preparation Robot with SampleRail / NMR or other Methods

25. Automatic Sample Preparation and Transfer Preparation Robot with

26. Example TECAN Workplate (for routine analytic)

27. TECAN Evo/SampleRail on an 800MHz System Pooling + Titration

28. Contacts sampletrack@bruker.de samplerail@bruker.de samplechanger@bruker.de