1. Overview of HIV/AIDS and ARV Treatment in Georgia
Lali Sharvadze MD, PhD
Director of inpatient Department .
Associated Professor.

2. Reported Cases of HIV/AIDS
in Georgia
2518
AIDS
538 - Deaths
Estimated number  3500

3. Distribution of HIV/AIDS Patients
by Sex and Age Groups
2518
Women 665
Men 1853
Age distribution

4. HIV Cases Registered in Georgia Annually
Number of cases

5. Distribution of HIV/AIDS Cases (number of registered cases)
by Regions of Georgia
(number of registered cases)
Abkhazia
168
891
Tbilisi
(55 Foreigners)
Svaneti 8
Lechkhumi 5
Samegrelo
369
Mtianeti 19
Poti 39
Imereti
319
Guria 54
Shida Kartli 66
Adjara
322
Kakheti
102
Samtskhe
Javakheti 29
Kvemo Kartli 94

6. Incidence of AIDS Cases
per population
(Source – WHO reports, 2007)

7. HIV Prevalence among High Risk Behavior Groups (2007)
HIV Prevalence in General Population

8. Distribution of HIV Cases by Routes
of Transmission

9. AIDS Control Service in Georgia
Country Coordinating Mechanism (CCM)
Infectious Diseases, AIDS & Clinical Immunology Research Center
National Center of Disease Control and Public Health
Zugdidi
AIDS treatment center
Batumi
AIDS treatment center
Kutaisi
AIDS treatment center
9 VCT centers in regions of Georgia
217 HIV diagnostic labs

10. Universal Access to HIV Treatment, Care and Support and Prevention
Georgia is the First Among
FSU Countries that from 2004 Ensured Universal (100%) Access to ARV Treatment.

11. What Does It Mean - The Universal (100%) Access to ARV Treatment Georgian Approach
Investigation of all HIV infected persons
by special algorithm
To identify all patients requiring ARV
treatment according to special criteria
To offer ARV therapy to all patients
requiring treatment
Monitoring of all patients receiving ARV treatment

12. according to WHO/UNAIDS/UNICEF report on universal access of 2008
Access to HAART
RUS*
BEL*
UKR*
KAZ*
GEO
UZB*
KGZ*
AZE*
ARM*
TKM
TJK*
ALB* FYM*
according to WHO/UNAIDS/UNICEF report on universal access of 2008
no HAART individuals on HAART (<1%) * in the process of scaling up ART
very poor access ( 1-25%) poor access (25-50%) disputed coverage estimates or
insufficient data available
moderate access (50-75%) good access (over 75%)

13. Implementation of Major Laboratory Methods
in Georgia
1984 – ELISA
1984 – Immunophenotyping of CD3, CD4, CD8 lymphocytes
1985 – Western blot
1995 – Qualitative PCR (Polymerase Chain Reaction)
1996 – Quantitative PCR (Polymerase Chain Reaction)
2003 – HIV and HCV Genotyping
2005 – HIV Genotypic Resistance Testing
HIV subtype analysis using phylogenetic methods
2006 – HIV, HCV & HBV quantitative- Real time PCR
2006 – CCR5, CCR2 and SDF1 genotyping testing
2009 – Abacavir hypersensitivity testing HLA-B*5701 SSP genotyping assay.

14. ARV implemented in Georgia
NRTI
AZT
3TC
D4T
DDI
Abacavir
Tenofovir
FTC
Téno/FTC Truvada®
ABC/3TC
Protease Inhibitors (PI)
Ritonavir Norvir®
Indinavir Crixivan®
Saquinavir Invirase®
Nelfinavir Viracept®
Lopinavir Kaletra ®
Atazanavir Reyataz®
Fosamprenavir Telzir ®
Tipranavir Aptivus®
Darunavir Prezista®
Entry inhibitor
Enfuvirtide
NNRTI
Nevirapine Viramune®
Efavirenz Sustiva®*
Integrase inhibitor
Raltegravir

15. 739 Patients are currently receiving ART
ARV Treatment
739 Patients are currently receiving ART
710
adults
29 children

16. National Guidelines Criteria for Initiation of Antiretroviral Therapy Based on WHO and DHHS ART Guidelines
History of an AIDS-defining illness;
CD4 T - cell count <350 cells/mm3;
Patients with HIV-associated nephropathy;
Patients co infected with HBV when treatment is indicated.

17. Georgian HIV/AIDS National Guidelines
updated annually

18. Thank you for your
attention!