1. Jacqui Patterson Interchurch Medical Assistance (IMA) CCIH, May 2003 The Diflucan Partnership Program: IMA & Pfizerwww.diflucanpartnership.org

2. Diflucan Partnership Program Pfizer providing Diflucan (fluconazole) free of charge to governments and NGOS for HIV/AIDS patients with life- threatening opportunistic infections Pfizer providing Diflucan (fluconazole) free of charge to governments and NGOS for HIV/AIDS patients with life- threatening opportunistic infections Program also includes training of health care professionals, patient education, and on-going monitoring and support Program also includes training of health care professionals, patient education, and on-going monitoring and support No time or cost limits No time or cost limits

3. Program Parameters Diflucan donation is for two indications: Cryptococcal meningitis Cryptococcal meningitis First line treatment of amphotericin B (IV drip in hospital) followed by Diflucan 200mg maintenance therapyFirst line treatment of amphotericin B (IV drip in hospital) followed by Diflucan 200mg maintenance therapy Esophageal candidiasis Esophageal candidiasis Diflucan 200mg for 14 daysDiflucan 200mg for 14 days

4. Diflucan Partnership Program Program Results since Launch (as of May 03) 16 countries launched to date: Botswana, The Gambia, Ghana, Haiti, Lesotho, Malawi, Botswana, The Gambia, Ghana, Haiti, Lesotho, Malawi, Namibia, Mozambique, Rwanda, South Africa, Swaziland, Namibia, Mozambique, Rwanda, South Africa, Swaziland, Tanzania, Uganda, Zambia, Zanzibar, Zimbabwe Tanzania, Uganda, Zambia, Zanzibar, Zimbabwe  86,000 prescriptions processed  2.5 million tablets dispensed  More than 11,000 health care workers trained

6. General Roles & Responsibilities DISTRIBUTION AGENT Stores tablets, IV and OS in warehouse Stores tablets, IV and OS in warehouse Ships products to recipients Ships products to recipients Tracks shipments Tracks shipments PROGRAM ADMINISTRATOR Processes Applications Processes Applications Communicates with potential recipients Communicates with potential recipients Manages External Review Committee Manages External Review Committee Provides recommendation to Pfizer Provides recommendation to Pfizer “Green Light” to IDA “Green Light” to IDA Tracks usage Tracks usage Manages reporting and resupply process Manages reporting and resupply process Directs NGOs & Governments to website www.diflucanpartnership.org Directs NGOs & Governments to website www.diflucanpartnership.org Reviews and approves recommendation from Axios Reviews and approves recommendation from Axios Coordinates quarterly shipping Coordinates quarterly shipping Guides training Guides training Develops monitoring & evaluation tools Develops monitoring & evaluation tools DONEE & OUTREACH Provides approval to IDA Provides approval to IDA Encourages member agencies in target countries to apply Encourages member agencies in target countries to apply Assists member agencies in application Assists member agencies in application

7. IMA’s Role Donation Processing Donation Processing Taking legal title to productTaking legal title to product Reviewing and approving applicationsReviewing and approving applications Direct Country Role – Haiti, DRC Direct Country Role – Haiti, DRC Facilitating Countries – Zimbabwe, Malawi, Zambia, Tanzania Facilitating Countries – Zimbabwe, Malawi, Zambia, Tanzania Monitoring and Evaluation Monitoring and Evaluation (con’t...)

8. IMA’s Role (con’t) Direct Country Role – Haiti, DRCongo Direct Country Role – Haiti, DRCongo Where IMA already has a country presence and programmatic strengthWhere IMA already has a country presence and programmatic strength Sharing information with local partnersSharing information with local partners Assisting with application for productAssisting with application for product Forging relationships with MoHsForging relationships with MoHs Materials disseminationMaterials dissemination (con’t...)

9. IMA’s Role (con’t) Facilitating Countries Facilitating Countries – Zimbabwe, Malawi, Zambia, Tanzania – Zimbabwe, Malawi, Zambia, Tanzania Meet with CHA/NGO networks (inform, review)Meet with CHA/NGO networks (inform, review) Identify interest groups for group applicationsIdentify interest groups for group applications Facilitate applicationsFacilitate applications Follow-up and technical assistanceFollow-up and technical assistance (con’t...)

10. IMA’s Role (con’t) Monitoring and Evaluation Monitoring and Evaluation Notify Pfizer of problems or challengesNotify Pfizer of problems or challenges Sharing facility locations for GIS mappingSharing facility locations for GIS mapping Obtaining anecdotal information, storiesObtaining anecdotal information, stories Partnering on writing about challenges, lessons learned, best practicesPartnering on writing about challenges, lessons learned, best practices

11. The Diflucan Partnership is “the first of, we hope, many other successful “the first of, we hope, many other successful public/private partnerships initiated public/private partnerships initiated by parties who have demonstrated by parties who have demonstrated that they care enough to act.” that they care enough to act.” Dr. Manto Tshabalala-Msimang, Minister of Health, South Africa