1.  Antibiotic Resistant Microorganisms Should we be concerned? The Story of A. baumanii, A.K.A., IRAQIBACTER, and other multi-drug resistant bacteria.

2. On the Trail of a Killer Microbe  Before there were antibiotics, war was often associated with disease epidemics.  http://www.pbs.org/wgbh/nova/sciencenow/0303 /video-extr-q-350-04.html http://www.pbs.org/wgbh/nova/sciencenow/0303 /video-extr-q-350-04.html  Open “Killer Microbe T-F”  Answer each statement as true or false. Do this in BLUE.

3. How do bacteria reproduce?  Which would you rather be given:  (a) $10 a day for one month; or  (b) one penny the first day of a month, double that amount on the second day, double that amount on the third day, and so on for the whole month.  Use the chart to calculate how much money you would have at the end of the month for each option. Which option gives you more $$$?

4. Killer Microbe - Video  Follow the link on my website to access the PBS website.  After watching the video, find a partner and correct your response sheet, this time in GREEN.  With your partner, read “Acinetobacter baumanii, Iraqibacter.  Answer the questions 3 and 4.

5. Map of A. baumanii infections

6. Development of Drug- Resistance  Unlike human beings who only pass genes from parent to offspring, bacteria have found several different ways to pass along their genes.  In recent years, scientists have learned that not only do mutations give bacteria their resistance to drugs, but resistance genes can be passed from one species of bacteria to a completely different species in a process called conjugation.

7. Bacterial  Animation showing the acquisition of bacterial resistance in S. pneumoniae, the most common cause of serious bacterial infection in the US.  http://www.pbs.org/wgbh/evolution/survival/clock / http://www.pbs.org/wgbh/evolution/survival/clock /  Watch the animation on bacterial conjugation.  http://www.hhmi.org/biointeractive/bacterial- conjugation http://www.hhmi.org/biointeractive/bacterial- conjugation

8. Reading  Read “Antibiotic Resistance”  Answer question 5.

9. Antibiotic-Resistant Staph  “Arms Race With a Superbug” Timeline  Answer questions 6 and 7

10. Tuberculosis  We will watch the video, “Why Does Evolution Matter Now”  http://www.pbs.org/wgbh/evolution/library/11/2/ e_s_6.html http://www.pbs.org/wgbh/evolution/library/11/2/ e_s_6.html  Answer questions 8, 9, and 10.

11. Public Health Alert  You and your partner will create a public health pamphlet or advertising slogan and campaign poster to alert the public about the potential problems caused by the overuse of antibiotics.  Explain that antibiotic resistance is often a result of overuse and misuse of antibiotics.  Include how hospitals and clinics play a role in creating antibiotic-resistant strains of bacteria  Include one example organism and the preventative measures that people can follow to avoid infection.