1. 1987-1995 a UNIDO special project 1995-today An independent international organization

2. The ICGEB mandate To provide a Centre of excellence for research and training in genetic engineering and biotechnology addressed to developing countries and economies in transition

3. 55 FULL MEMBER STATES

4. 71 SIGNATORY COUNTRIES

5. The ICGEB structure ICGEB is one Centre, made of two Components and a network of Affiliated Centres Trieste Component (Italy) New Delhi Component (India) ICGEB

6. Trieste to Venice to Pula (Croatia) to Austria Piran (Slo)

7.  In-house research projects  Long-term post-doctoral fellowships  Short-term fellowships  Ph.D. Program  Organization of meetings, courses and workshops  Collaborative Research Funding Program  Collaboration with industrial sector  Scientific services to Member Countries I NSTRUMENTS OF A CTION

8. Workshops and Courses Member Country Research Laboratories Member Country Research Laboratories ICGEB Basic and Applied Research Institutional and Scientific Services Technology Transfer Research Grants Pre- and Post-Doc Fellowships Trained Scientists

9. ICGEB: activity 1988-2005 Publications in peer- reviewed international journals 1383 Long-term fellowships 504 awarded 880 man/year Short-term training5480 persons trained Research grants 262 awarded For a total of USD 12,343,780 Patents 34 filed Technology Transfer Agreements 72 signed

10. 2006 BUDGET TOTAL = 15,569,000 €

11. 2006 BUDGET TOTAL = 15,569,000 €

12. ICGEB: Instruments of action In-house research projects Long-term post-doctoral fellowships Short-term fellowships Ph.D. Program Organization of meetings, courses and workshops Collaborative Research Granting Program Collaboration with industrial sector Scientific services to member Countries

13.  Human Health ( Basic and applied research in infectious diseases and the genetic component of tumors and cardiovascular pathologies)  Crop improvement (Biotic and abiotic stress, plant transformation, insect resistance, biopesticides)  Biosafety risk assessment  Technology development and transfer  Cooperation with other UN bodies R ESEARCH AND D EVELOPMENT F OCUS

14. ICGEB Trieste Research Program l Molecular Medicine (gene therapy of cardiovascular disorders, HIV infection) l Molecular Pathology (genetic disorders, regulation of mRNA processing) l Molecular Immunology (genetics of antibodies, molecular biology of rotavirus) l Virology (papillomavirus and cell cycle regulation) l Bioinformatics and protein structure l Microbiology l Proteomics l Biotechnology

15. Delhi Component Research & Development Focus Human Health (Basic and applied research in infectious diseases & structural biology) Agriculture ( Biotic and abiotic stress, plant transformation, insect resistance, biopestcides etc) Technology development and transfer

16. Vaccine Related Research Malaria vaccine research Hepatitis B & E Dengue viral infection (vaccines and diagnostics) Tuberculosis ( basic immunology & vaccine research ) Technology development and transfer

18. ICGEB: Instruments of action In-house research projects Long-term post-doctoral fellowships Short-term fellowships Ph.D. Program Organization of meetings, courses and workshops Collaborative Research Granting Program Collaboration with industrial sector Scientific services to member Countries

19. COLLABORATIVE RESEARCH PROGRAMME (1999-2005)

23. ICGEB: Instruments of action In-house research projects Long-term post-doctoral fellowships Short-term fellowships Ph.D. Program Organization of meetings, courses and workshops Collaborative Research Granting Program Collaboration with industrial sector Scientific services to member Countries

24. NUMBER OF TRAINEE/YEAR FUNDED (1989-2004)

25. GEOGRAPHICAL DISTRIBUTION OF FELLOWSHIPS FUNDED (1989-2004)

26. 2005 FELLOWSHIP PROGRAMME 32 NEW FELLOWSHIPS AWARDED: 19 PRE-DOCTORAL 13 POST-DOCTORAL CURRENTLY, 75 FELLOWS ON BOARD

27. ICGEB: Instruments of action In-house research projects Long-term post-doctoral fellowships Short-term fellowships Ph.D. Program Organization of meetings, courses and workshops Collaborative Research Granting Program Collaboration with industrial sector Scientific services to member Countries

28. ICGEB meetings and courses participants 1988-2004 (Member States/Signatory Countries nationals and ICGEB scientists) EL June 2005

29. ICGEB meetings and courses participants 1988-2004 (Member States/Signatory Countries nationals and ICGEB scientists) EL June 2005

30. Meeting proposals received (annual calls 1988-2006) EL June 2005

31. Meetings hosted by Affiliated Centres in Member States 1988-2005 EL June 2005

33. ICGEB: Instruments of action In-house research projects Long-term post-doctoral fellowships Short-term fellowships Ph.D. Program Organization of meetings, courses and workshops Collaborative Research Granting Program Collaboration with industrial sector Scientific services to member Countries

34. International Center for Genetic Engineering and Biotechnology Fondazione Cassamarca ICGEB Biosafety Outstation at Ca’ Tron

35. Biosafety Unit What role does ICGEB play in Biosafety Dissemination of information  Biosafety Bibliographic Database  Risk Assessment Searching Mechanism (RASM)  GMO RES COM  Publications  WebPages and Biosafety News Capacity building  Biosafety annual workshops  Biosafety Research at our Outstation in Ca’ Tron  Co-operation and training with Member State biosafety authorities in biosafety and risk assessment  Construction of the Italian national BCH International co-operation  Voluntary Code of Conduct (1991)  Co-operation with UNIDO, UNESCO, UNEP, FAO, and CBD-Biosafety Clearing-House (BCH)  Participation in Inter-Agency Network for Biosafety (IANB)

36. ICGEB TO ASSIST THE UN SECRETARIAT IN FULFILLING THE MANDATE RECEIVED FROM THE SECURITY COUNCIL TO REINFORCE ETHICAL NORMS AND THE CREATION OF CODES OF CONDUCT FOR SCIENTISTS THROUGH INTERNATIONAL AND NATIONAL SCIENTIFIC SOCIETIES AND INSTITUTIONS THAT TEACH SCIENCES OR ENGINEERING SKILLS RELATED TO WEAPONS TECHNOLOGIES

37. RELATIONSHIP WITH OTHER INTERNATIONAL ORGANISATIONS

40. PARAGRAPH 10: AS THE ONLY OPERATING LABORATORY IN THE FIELD OF GENETIC ENGINEERING AND BIOTECHNOLOGY WITHIN THE UNITED NATIONS SYSTEM, AND AS A MAJOR TRAINING AND INFORMATION RESOURCE FOR DEVELOPING COUNTRIES, THE ICGEB UNDERTAKES A SPECTRUM OF ACTIVITIES REFLECTING ALL FIVE PROGRAMME AREAS [OF AGENDA 21]. AS A TECHNICAL ARM, IT IS CLEARLY IN A POSITION TO CLOSELY COLLABORATE WITH OTHER AGENCIES IN FIELDS SUCH AS INNOVATION DEVELOPMENT, BIOSAFETY, TECHNOLOGY TRANSFER, INVESTMENT STRATEGIES AND MANAGEMENT, INCLUDING THE DEVELOPMENT, ACQUISITION AND COMMERCIALIZATION OF BIOTECHNOLOGY PRODUCTS, SERVICES AND INDUSTRIAL PROCESSES, AS WELL AS IN GLOBAL BIO-INFORMATIC NETWORKING. Other references in paragraphs 6, 12, 21, 30, 50, 51, 52, 53, 54, 79 & 80

41. http://www.icgeb.org

42. TERMS OF SERVICE OF THE REMAINING TEN MEMBERS OF THE CSA NEW DELHI, 16 FEBRUARY 2005

43. “WE NOTE CONTINUING WORK TO EXPLORE ESTABLISHING AN INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY CENTRE [COMPONENT] IN AFRICA, TO HELP RESEARCH INTO VACCINES FOR THE DISEASES THAT ARE AFFLICTING THE CONTINENT”.

44. “WE SUPPORT THE ESTABLISHMENT OF THE THIRD COMPONENT OF THE INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY IN AFRICA”. SECOND AFRICAN MINISTERIAL CONFERENCE ON SCIENCE AND TECHNOLOGY (DAKAR, SENEGAL, 26-30 SEPTEMBER 2005)

45. WHY? SET-UP OF A CRITICAL MASS DEMAND-DRIVEN RESEARCH AND TRAINING PROGRAMMES PROVIDE ACCESS TO TECHNOLOGIES DEVELOP ENTREPRENEURSHIP AND INDUSTRY/LABORATORY RELATIONS ACT AS A CLEARING HOUSE FOR THE REGION ENSURE ADEQUATE SYNERGIES WITH THE AAB AND THE ICGEB AFFILIATED CENTRES MULTIPLYING EFFECT WITH TRIESTE AND NEW DELHI.

46. AND AN ICGEB COMPONENT IN LATIN AMERICA?