1. Do NOW: In your notebook, compare and contrast DNA and RNA HW out on desk!!

2. RNARNA

3. What is RNA? Ribonucleic acid is genetic information. It is similar to DNA because it is also made of a sugar phosphate backbone and nitrogenous bases.

4. The structural differences between DNA and RNA 1.Sugars - DNA has Deoxyribose in its backbone (has 1 less oxygen) - RNA has Ribose in its backbone.

5. The structural differences between DNA and RNA 2. Nitrogenous Bases - DNA has Thymine - RNA has Uracil They both have Adenine, Cytosine, and Guanine

6. The structural differences between DNA and RNA 3. Structure - DNA is a double strand - RNA is a single strand This allows RNA to leave the nucleus

7. Amino Acid A compound with an amino group (-NH 2 )on one end and a carboxyl group (-COOH) on the other end A subunit (monomer) from which proteins (polymers) are assembled

8. Proteins Polymers made up of amino acids that perform a wide variety of cellular functions Linked together by peptide bonds Also called polypeptides One of the classes of organic macromolecules that function as structural and control elements in living systems Needed by the body for: – Growth and repair – To make up enzymes (Biological catalysts)

9. Play Video DNA to Protein

10. Online Activity Go to: http://learn.genetics.utah.edu/content/begin/ dna/transcribe/ http://learn.genetics.utah.edu/content/begin/ dna/transcribe/ Read the directions carefully and perform the activity. You will transcribe and translate a gene!

11. Do NOW: In your notebook, explain transcription and translation. HW out on desk!!

15. Types of RNA 1. Messenger RNA - mRNA - carries genetic information from the nucleus to the ribosome for protein synthesis

16. Types of RNA 2. Ribosomal RNA - rRNA - carries genetic information for making new ribosome

17. Types of RNA 3. Transfer RNA - tRNA -Matches with mRNA during translation - Connected to amino acids -Amino acids of neighboring tRNA form a chain to make proteins

18. DNA Transcription

19. Description DNA transcription is the process of creating messenger RNA (mRNA). Location DNA transcription occurs in the nucleus because that is where DNA is located.

20. How Transcription Works 1. The DNA strand unwinds 2. Complementary RNA nitrogenous bases match up with one side of the DNA strand 3. The RNA is released from the DNA strand. 4. The DNA rewinds. 5. The mRNA leaves the nucleus.

22. Translation and Protein Synthesis

23. Interpreting the mRNA Strands of mRNA are divided into sections of 3 nitrogenous bases called codons. Codon – 3 bases that code for a specific amino acid.

24. Characteristics of tRNA tRNA has anticodons that compliment the mRNA codons tRNA is attached to an Amino acid that will form a protein chain.

25. Translation and Protein Synthesis Translation is the process of translating the genetic code of mRNA into tRNA. Protein Synthesis is the process of amino acids connected to tRNA bonding to form a protein. Translation and Protein Synthesis happen simultaneously.

26. Steps in Translation and Protein Synthesis 1.mRNA enters the ribosome 2.Complimentary tRNA attaches to the start codon on mRNA 3.The mRNA moves through the ribosome

27. Steps in Translation and Protein Synthesis (continued) 4.The next mRNA codon is matched with the complimentary tRNA 5.Amino acids connected to both tRNA strands connect to each other

28. Translation – Protein Synthesis (continued) 6.The process continues until a stop codon is reached, releasing the protein.

30. Study Guide Expectations Groups of 3 (you choose)! Responsibilities – Create a Review packet for Test 2! – 1  Cell Cycle (Mitosis, Meiosis) – 2  DNA Structure, DNA Replication, History – 3  RNA vs DNA Comparison, Transcription, Translation 1 hr – Work on own section for 20 min  Rotate – Read/edit/add to section 15 min  Rotate – Read/edit/add to section 15 min – Last 10 minutes  compile and PRINT (4 copies) 1 copy for each team member, and one to turn in to the teacher – If you finish early, quiz each other!