1. © NIH National Center for Image-Guided Therapy, November, 2008 Visualization of DTI Tractography while Tracking by BrainLab System Haiying Liu Surgical Planning Lab Brigham & Women's Hospital Harvard Medical School

2. © NIH National Center for Image-Guided Therapy, November, 2008 Acknowledgements National Center for Image Guided Therapy NIH U41RR019703 NEDO Intelligent Surgical Instruments Project

3. © NIH National Center for Image-Guided Therapy, November, 2008 The Team Haiying Liu, BWH Noby Hata, BWH Alex Golby, BWH Junichi Tokuda, BWH Steve Pieper, Isomics Xenios Papademetris, Yale Pratik Patel, BrainLab AG

4. © NIH National Center for Image-Guided Therapy, November, 2008 Assertion Only the setup and testing of the system in last two sections have been successful can we start to perform the following fiducial seeding for DTI tractography.

5. © NIH National Center for Image-Guided Therapy, November, 2008 Outline Load tensor image Create a fiducial list Configure Tractography module Configure NeuroNav module

6. © NIH National Center for Image-Guided Therapy, November, 2008 Load Tensor Image Go to Volumes module to load the tensor image

7. © NIH National Center for Image-Guided Therapy, November, 2008 Create a Fiducial List Move your mouse into any 2D slice window and then press P key while holing left mouse button. You will see a fiducial right way, which is named L-P

8. © NIH National Center for Image-Guided Therapy, November, 2008 Configure Tractography Module Go to Fiducial Seeding by the following sequence: Modules -> Tractography -> Seeding -> Fiducial Seeding In the tab of Tractography Seeding From Fiducial – Set L for Select FiducialList or Model – Set Create New Fiber Bundle for Output Fiber Bundle Node

9. © NIH National Center for Image-Guided Therapy, November, 2008 Configure Tractography Module Set two values

10. © NIH National Center for Image-Guided Therapy, November, 2008 Configure NeuroNav Module Set the node name to BioImageSuite Click this button to start seeding

11. © NIH National Center for Image-Guided Therapy, November, 2008 Result At this point, you should see fiducial seeding of DTI tractography on fly. Check the tutorial for comparison.