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Protein Synthesis
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Codes! DNA contains codes Codons Sequence of amino acids = proteins
3 nucleotide bases = amino acid Sequence of amino acids = proteins DNA copied = mRNA (messenger RNA)
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Transcription and Translation
Creation/synthesis of mRNA from a DNA template strand Translation Ribosomes make proteins using the mRNA strand made by transcription
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Transcription One strand of DNA is copied Creates mRNA
mRNA travels OUT of the nucleus to the cytoplasm (where the ribosomes are)
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mRNA Ribonucleic Acid Structurally similar to DNA
U instead of T Single-stranded Used to create proteins AUGACGGUU
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Vocab Codon Amino Acid Basic unit of the genetic code
Sequence of 3 adjacent neucleotides in DNA or mRNA Amino Acid RNA codon
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Translation 3 Main Steps
Initiation Elongation Termination
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Translation Steps Initiation
Ribosomes attach to an mRNA strand
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Translation Steps Elongation
Translation begins at the AUG codon AUG means GO!
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tRNA Molecules tRNA Recognize both specific mRNA codons and the amino acids that match those codons Contains an “anti-codon” which attracts specific amino acids Similar to the complimentary base pairing rule
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Translation Steps Elongation
Transfer RNA (tRNA) molecules carry anti-codons These anti-codons find complimentary codons and attach them to the ribosome and mRNA
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Translation Steps Elongation
The ribosome travels down the mRNA and reads the codons
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Translation Steps Elongation
The ribosome pauses at each codon and waits for the tRNA to bring the correct amino acid Each amino acid is bound together by a Peptide Bond!
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Translation Steps Termination
The process continues until the ribosome reaches a stop codon
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Translation Steps Termination
Everything breaks apart! Final peptide bonds are created, the ribosome breaks apart, and the polypeptide (protein) is released
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Translation Steps Termination
The Protein (polypeptide) folds into its specific shape. Shape determines function! The Protein is ready to be used by the body!
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64 codons code for 20 different amino acids
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