1. Second meeting of Working Group on Advance Market Commitments (AMCs) London, 9 November 2006 Mark Bowman Director, International Finance

2. Introduction Rome agreement to meet again for more technical discussions on the design of a Pneumococcus AMC World Bank and GAVI have produced a Framework Document to underpin discussions Framework Document sets out key elements of AMC structure

3. Structure of todays meeting Pneumococcus burden and vaccine development Market modelling and value for money Institutional and governance framework Financing arrangements Timetable Conclusions

4. Objectives of meeting Hear, and exchange, views on the model set out in the Framework Document Form consensus on design issues Identify any challenges going forward Discuss next steps