1. Biology in Your World Preserving Our Environment Overpopulation – over 7 billion people on Earth! Has a significant impact on other organisms and the environment Tropical Rain Forest Destruction - Home to many species of plants and animals - Potential medicines and new foods

2. Other Environmental Issues: Conservation and preservation Global warming Ozone depletion Acid rain Endangered species AND......

3. Improving the Food Supply Genetic engineering of crop plants (GM) - transfer genes from one kind of organism to another Has created plants: Resistant to herbicides Poisonous to insect pests but not humans New varieties with improved nutrition and protein content ex. Rice with genes that increased vitamin A and iron

4. Understanding the Human Genome Genome - complete genetic material (DNA) contained in an individual Human Genome Project “completed” 6/26/2000 The Human Genome contains: 3 billion pairs of nucleotides. Have identified most human genes Much research still needed to lead to: cures and therapy treatment new medicines

5. Fighting Disease AIDS (acquired immune deficiency syndrome) HIV (human immunodeficiency virus) - the virus that causes AIDS by attacking and destroying the immune system Have developed a combination of drugs to slow progression No vaccine yet - virus mutates rapidly

6. Cancer - a tumor in which the cells begin dividing at an uncontrollable rate and become invasive Results from a breakdown in the controls for cell division Many types of cancer can be treated if detected early Progress in cures for cancer

7. Emerging Diseases Increase in infection because of overpopulation and ease of transportation. Ex.

8. Swine Flu

9. Gene therapy - replacement of a defective gene with a normal version of the gene Clinical trials for: cystic fibrosis - a fatal genetic disorder in which excessive amounts of mucus are secreted, blocking intestinal and lungs (bronchial ducts) and causing difficulty in breathing and digestion

10. Embryonic Stem Cell Research

11. Organ Transplants

12. Cloning

13. Common stages of the “scientific method” – organized approach to solving a problem 1.Observations 2.Asking questions 3.Forming Hypothesis 4.Making predictions 5.Confirming predictions with experiments 6.Drawing conclusions

14. Observation – the process of obtaining information by using the senses Asking Questions –observations raise questions Hypothesis – an explanation that is based on observations and that can be tested Prediction – a statement made in advance that expresses the results that will be obtained from testing a hypothesis (if the hypothesis is supported) WHY?

15. Confirming predictions by: Performing an experiment Experiment – a procedure that is carried out under controlled conditions to discover, demonstrate or test a fact, theory or general truth Controlled experiment – an experiment set up in duplicate in which a single factor is changed in one set up but not the other Control group – the part of an experiment that does NOT contain the variable Experimental group - the part of an experiment that contains the variable being tested

16. Variable – single factor that is isolated and tested in an experiment Independent variable – the factor that is deliberately manipulated in the experiment ex. Dependent variable – in an experiment, the variable that is changed or determined by manipulation (of one or more factors); RESULTS ex.

17. Drawing Conclusions Data is collected and analyzed, and then a conclusion is made as to whether data supports the hypothesis Hypothesis may be supported or rejected

18. A Case Study: John Harte’s Study on Tiger Salamanders in the Rockies Collecting Observations: John Harte (1984-1988) observed a decline of tiger salamanders in the Rockies David Bradford (1988) observed that 98% of frogs had disappeared from lakes in the Sequoia and Kings Canyon National Parks Reported observations to other biologists and found that amphibian elsewhere were declining

19. Harte had studied salamanders for years: knew their behavior, diet, reproduction, etc. He visited their ponds regularly and sampled the water. Rocky Mountain precipitation is acidic

20. Asking Questions WHY are the number of salamanders dropping? WHY is Rocky Mountain precipitation acidic and more acidic in May? Power plants release pollutants that cause acid precipitation In the spring, snow melts and releases high levels of acid (all the winters snow)

21. Forming Hypotheses and Making Predictions Harte’s 2 hypotheses: 1. Acids formed in the upper atmosphere by pollutants were falling as acid precipitation in the mountains in the winter snows. 2.Melting snow in spring makes ponds suddenly acidic and harms salamander embryos. Expected outcome if Harte’s hypothesis is accurate 1.Would find increased acidity in ponds after snow melts. 2.There would be enough acid in ponds to harm embryos.

22. Confirming Predictions - Experiment Harte gathered data from many years of observations on the pH of ponds. pH – a value used to express the acidity or alkalinity (base) of A solution; scaled From 0 to 14 Data confirmed the 1 st prediction: Melting snow caused Increased acidity In ponds

23. Harte performed a controlled experiment 1.Allowed captive salamanders to: lay eggs in regular pond water 2.Collected and divided eggs into 5 groups: Control group: eggs placed in pond water with neutral pH 4 experimental groups: eggs placed in pond water with different acidic pH VARIABLE IS :_________ 3. Found that: Many salamanders never hatched from eggs in acidic water Some that did hatch had developmental abnormalities

24. Drawing Conclusions Harte’s data supported his hypothesis (for Tiger Salamanders in the Rockies) Viewing Conclusions in Context Scientists are working together to determine the cause of the global decline of amphibians Have found (through more experiments): Chemical pollutants (acid rain) enter through skin Habitat destruction Non-native species outcompeting local populations Amphibians have a high rate of fatal infections by parasites

25. Theory –a set of related hypotheses that have been tested and confirmed many times by scientists (an explanation for some phenomenon that is based on observation, experimentation and reasoning) A theory unites and explains a broad range of observations Ex.Cell theory Germ Theory of Disease