1. Why do some allergens effect different people in different ways?
Deanna Dailey
Dr. Chan’s Human Phys G Block

2. What is an allergic reaction?
An allergic response is when an antibody binds to and antigen and irritation occurs.
Types of reactions:
Rash or hives
Swelling: epically of the lips, tongue, throat, face
Dizziness
Nausea/ diarrhea
Anaphylaxis

3. Steps to an allergic reaction
The antigen enters the body
Triggered B-cells to produce IgE antibodies
These antibodies target the specific allergen
This releases histamine to battle the allergen causing a reaction.
Depending on how sensitized, the genes of the person, or how much histamine is released, the person can have a mild or major reaction.

4. Why are there different effects?
Genes
MHC
Controlled by different genes and they have many different variations.
Socioeconomic background
Immunity towards allergens was a defense mechanism
Variation in total and specific IgE: effects of ethnicity and socioeconomic status
Exposure
The more you are exposed, the worse the symptoms can be.

5. Works Cited