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Headings Vocabulary Important Information
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Terminology Tissues – group of cells that carry out specialized activities Histo = Tissue …ology = study of Pathologists – Study of cells and tissue; diseased Patho = disease *
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Four Main Types Epithelial Connective Muscle Nervous
Body surfaces, hollow organs, glands Connective Binds organs together, energy reserves for fat Muscle Movement and force application Nervous Stimulates action potential to activate body functions *
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Germ Layers Ectoderm – The primary layer which give rise to nervous system and the epidermis of skin Mesoderm – Middle germ layer which gives rise to connective tissue, blood, muscles Endoderm – Lower germ layer that gives rise to the GI tract, urinary bladder, and respiratory tract *
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Cell Junctions – Point of contact between adjacent membranes of various cell types
Tight Junctions – Fluid tight seal between cells to prevent leaking of substances into blood or surrounding tissues; stomach lining & urinary bladder, and intestines *
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Anchoring (Adhesion) Junction (Desmosomes)
– Fasten cells to on another, common in stretched areas such as heart uterus outer skin
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Gap Junction Allow passage of chemical/electrical signals through connexons (protein tunnels-hollow cylinders) from cell to cell; i.e. muscular contraction, pain
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Protection, Filtration, Secretion, Absorption, and Excretion
Functions: Protection, Filtration, Secretion, Absorption, and Excretion Divisions: Covering and Lining 2.Glandular Epithelium *
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Tissue Arrangements Layer Arrangement Simple Stratified
Pseudostratified Single Layer Two or More layers One layer of mixed cells Osmosis, Diffusion, Absorption, Secretion Protect underlying tissues In areas of wear and tear Mucus Secretion And Movement *
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Cell Shapes Cell Shapes Squamous Cuboidal Columnar Transitional Flat
Thick Cubed Tall, Cylindrical Varies *
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A. Simple Squamous Function: Filtration, diffusion, osmosis, and secretion in serous membranes Location: Kidneys Glomeruli (water, glucose, and wastes), Air Sac of Lungs (Gas Exchange), Heart and Blood Vessels (Nutrients & Medicine) *
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B. Simple Cuboidal Function: Secretion and Absorption
Location: Kidney Tubules (Wastes), Ovary Surface (Ova) *
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C. Ciliated Simple Columnar
Function: Moves fluids and particles along passageways Location: Found in respiratory tract (mucosal Movement), fallopian tubes (Ova movement), sinuses (Pathogen removal→ Runny Nose) Cilia *
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C. Non-Ciliated Columnar
Function: Microvilli secretion and Absorption Location: GI tract lining (Absorption of nutrients and water) & Gallbladder (Secretion of Bile) *
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A. Pseudostratified Columnar Epithelium
Functions: Mucus movement by cilia action Location: Found in upper respiratory tract and urethra, and gonads of males (Sperm maturation) *
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B. Stratified Squamous Functions: Protection of superficial layers of skin; vagina, mouth, esophagus, tongue Location: Keratinized = Superficial Layers of Skin Non-Keratinized = Wet Surfaces (Mouth, Vagina, Tongue) *
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C. Stratified Cuboidal Functions: Protection and limited secretion of sweat glands Location: Sudoriferous Glands (SWEAT) *
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D. Transitional Epithelium
Function: Accommodate Distension in the urinary tract and vaginal walls as fluid pressures vary. Stretched = Squamous Relaxed = Cuboidal Location: Lining of the ureters, urethra, and bladder *
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Glandular Epithelium
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A. Glandular Epithelium: Endocrine
Function: Produce hormones Location: Thyroid, Pituitary Gland, Ovaries,Testicles *
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B. Exocrine Glands Merocrine (or Eccrine) secretion Apocrine secretion
Forms the product and discharge from the cell entirely Salivary Glands Apocrine secretion Product forms at apical surface and pinches off from rest of cell Mammary gland Holocrine secretion Accumulates secretory product in cytosol, cell dies and is discharge with its product Sebaceous Gland (Acne) *
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Binds organs together, energy reserves for fat
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Connective Tissue Three basic characteristics- 1.Cell Types
Fibroblasts – Large, flat immature cells responsible for mitosis & chemical secretion of matrix compds Macrophages – Fixed vs. Wandering = Local or systemic Phagocytosis Plasma Cells – Synthesis of B Lymphocoyte ~ Antibodies Mast Cells – Histamine production, Heparin & Warfarin (Anticoagulants) *
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2.Ground Substance (Matrix)
Hyaluronic Acid Cell binding, wound healing Chondroitin Sulfate Adhesiveness for bone, cartilage Dermatan Sulfate skin, tendons, heart valves Keratan Sulfate Bone, Cartilage
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3.Fibers (Matrix) Collagen – Strength for tissues, most abundant Elastin – Elasticity of tissues up to 150% of normal size
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Skeletal Muscle Tissue Areolar Loose Con. Tissue
Hyaline Cartilage Cardiac Muscle Skeletal Muscle Tissue Areolar Loose Con. Tissue Simple Cuboidal Epithelium Adipose Loose Con. Tissue Nervous Tissue Stratified Squamous Epithelium Smooth Muscle Tissue Bone Connective Tissue
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Provides for support, Movement-Marrow (blood-forming)
Calcium Haversian Canal Compact vs. Spongy Provides for support, Movement-Marrow (blood-forming) *
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Cartilage
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Extremely strong, but very flexible and elastic
Chondrocyte Ground Substance Lacuna Extremely strong, but very flexible and elastic Smooth surface for reduction of friction Movement of Joints, Flexibility Support (Trachea), Ossification *
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Fibrocartilage Extremely tough Acts as a shock absorber
Ex: ball and socket joints, intervertebral disc *
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Elastic Cartilage Abundance of elastin for stretching capability
Nose, Ears, epiglottis, larynx
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Dense Fibrous Connective Tissue
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Dense, Closely packed collagen fibers that provide high tensile strength
Strong attachment for Tendons (Muscle to Bone), Ligaments (Bone to Bone) *
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Loose Connective Tissue
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Consists of Collagen, Elastic, Reticular fibers
Fibroblasts Elastin Collagen Provides strength, elasticity, and support to subcutaneous layer and pappilary regions of skin Consists of Collagen, Elastic, Reticular fibers *
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Nucleus Fat Storage Blood Vessel Insulation Energy Reserves *
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Adipose Fat (White): Used for insulation, energy reserve, fat storage
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Adipose Fat (Brown): Generates body heat in newborns that do not shiver After infants grow up, most of the mitochondria (gives the brown color) disappears, becomes similar to white fat. Recent Research=brown fat is related not to white fat, but to skeletal muscle
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Loose Conn. Tissue Reticular Cartilage
Reticular – Form covering of many internal organs (Stroma)
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Clotting (platelets) Immunity (WBC’s) Nutrient delivery
Oxygen Transport Clotting (platelets) Immunity (WBC’s) Nutrient delivery *
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Movement and force application
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Composes the heart wall
Functions in pumping blood to all parts of the body Intercalated discs contain Gap Junctions (Communication) & Desmosomes (Anchor) *
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Skeletal Muscle Tissue
Attached to bones by tendons Functions in body movements, posture, thermogenesis Only Muscle tissue controlled voluntarily *
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Smooth Muscle Tissue Forms walls of many internal organs ie: Stomach, GI tract, Uterus, Anus Functions in motion of internal organs *
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Axon Dendrite Nucleus Consists of Neuron and Neuroglia
Neuron – Conversion from stimulus response to action potential (Sensory, Motor, Interneuron) Dendrites – Reacts to stimuli Axons – Conductor of impulse Axon Dendrite Nucleus *
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Sad? Need a Tissue? *
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Skeletal Muscle Tissue Areolar Loose Con. Tissue
Hyaline Cartilage Cardiac Muscle Skeletal Muscle Tissue Areolar Loose Con. Tissue Simple Cuboidal Epithelium Adipose Loose Con. Tissue Nervous Tissue Stratified Squamous Epithelium Smooth Muscle Tissue Bone Connective Tissue
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SIMPLE COLUMNAR EPITHELIUM
SIMPLE SQUAMOUS SIMPLE COLUMNAR EPITHELIUM TRANSITIONAL EPITHELIUM PSEUDO-STRATIFIED CILIATED COLUMNAR EPITHELIUM DENSE REGULAR FIBROUS TISSUE (TENDON)
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