1. Prednisone

2. Production
Prednisone is a man-made steroid and is used to treat many illnesses.
Prednisone is synthesized from cortisone by adding a double bond between C1 and C2.
Cortisone is synthesized from cholesterol in the outer layer, or cortex, of the adrenal gland under the stimulation of adrenocorticotropic hormone (ACTH)
Prednisone can be synthesized by microbiological dehydrogenation of cortisone

3. Cortisone to Prednisone

4. Composition Prednisone is made of C21H26O5
Chemically, it is 17,21-dihydroxypregna-1, 4-diene-3,11, 20-trione
Prednisone is a white to practically white, odorless, crystalline powder and has a molecular weight of It melts at about 230°C with some decomposition. Prednisone is very slightly soluble in water, slightly soluble in alcohol, chloroform, dioxane, and methanol.

5. Composition Cont. The Inactive Ingredients of Prednisone
5 mg of prednisone is made of: anhydrous lactose, colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, and talc.  

6. Composition
Carbon, Hydrogen and Oxygen are the main elements in prednisone.
Carbon is found in the non-metal section of the periodic table, hydrogen in the noble gases, and oxygen in the non-metals.

7. How it works
Prednisone is part of a group of medications called glucocorticoids.
glucocorticoids have numerous affects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties.
This drug works for most conditions by decreasing inflammation or suppressing an overactive immune system.
It works in myasthenia gravis(MG) by changing the normal action of the body’s immune system.

8. How it works cont. Prednisone is a man-made replica of cortisone
Cortisone is a steroid that is produced by the outer portion of adrenal glands
Cortisone normally helps regulate the body's salt and water balance and reduces inflammation.
The adrenal glands normally produces an amount of steroids equivalent to about 5 mg. of prednisone a day.
When prescribed in doses that exceed natural levels, prednisone suppresses inflammation and can help treat a variety of diseases.

9. Side Effects of Prednisone
Common side effects:
Nausea
Vomiting
loss of appetite
Headache
Dizziness
Extreme changes in mood
Changes in personality
Weight Gain
Bulging eyes
Thin, fragile skin
Increased hair growth
Extreme tiredness
Weak muscles
Heartburn
Trouble sleeping
Increased sweating
Acne
Moon face