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Meiosis Chapter 10
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Sexual Reproduction Chromosomes are duplicated in germ cells
Germ cells undergo meiosis and cytoplasmic division Cellular descendents of germ cells become gametes Gametes meet at fertilization
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Asexual Reproduction Single parent produces offspring
All offspring are genetically identical to one another and to parent
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Sexual Reproduction Involves
Meiosis Gamete production Fertilization Produces genetic variation among offspring
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Homologous Chromosomes Carry Different Alleles
Cell has two of each chromosome One chromosome in each pair from mother, other from father Paternal and maternal chromosomes carry different alleles
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Sexual Reproduction Shuffles Alleles
Through sexual reproduction, offspring inherit new combinations of alleles, which leads to variations in traits This variation in traits is the basis for evolutionary change
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Gamete Formation Gametes are sex cells (sperm, eggs)
Arise from germ cells ovaries anther testes ovary Figure 10.2a Page 164
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Chromosome Number Sum total of chromosomes in a cell
Germ cells are diploid (2n) Gametes are haploid (n) Meiosis halves chromosome number
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Meiosis: Two Divisions
Two consecutive nuclear divisions Meiosis I Meiosis II DNA is not duplicated between divisions Four haploid nuclei form
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Meiosis I In-text figure Page 165 Each homologue in the
cell pairs with its partner, then the partners separate In-text figure Page 165
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Meiosis II The two sister chromatids of each duplicated chromosome are separated from each other two chromosomes (unduplicated) one chromosome (duplicated) In-text figure Page 165
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Meiosis I - Stages Prophase I Metaphase I Anaphase I Telophase I
Figure 10.4 Page 167
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Prophase I Each duplicated chromosome pairs with homologue
Homologues swap segments Each chromosome becomes attached to spindle Figure 10.4 Page 167
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Metaphase I Chromosomes are pushed and pulled into the middle of cell
The spindle is fully formed Figure 10.4 Page 167
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Anaphase I Homologous chromosomes segregate
The sister chromatids remain attached Figure 10.4 Page 167
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Telophase I The chromosomes arrive at opposite poles
Usually followed by cytoplasmic division Figure 10.4 Page 167
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Prophase II Microtubules attach to the kinetochores of the duplicated chromosomes Figure 10.4 Page 167
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Metaphase II Duplicated chromosomes line up at the spindle equator, midway between the poles Figure 10.4 Page 167
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Anaphase II Sister chromatids separate to become independent chromosomes Figure 10.4 Page 167
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Telophase II The chromosomes arrive at opposite ends of the cell
A nuclear envelope forms around each set of chromosomes Four haploid cells Figure 10.4 Page 167
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Crossing Over Each chromosome becomes zippered to its homologue
All four chromatids are closely aligned Nonsister chromosomes exchange segments Figure 10.5 Page 168
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Effect of Crossing Over
After crossing over, each chromosome contains both maternal and paternal segments Creates new allele combinations in offspring
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Random Alignment During transition between prophase I and metaphase I, microtubules from spindle poles attach to kinetochores of chromosomes Initial contacts between microtubules and chromosomes are random
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Random Alignment Either the maternal or paternal member of a homologous pair can end up at either pole The chromosomes in a gamete are a mix of chromosomes from the two parents
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Possible Chromosome Combinations
As a result of random alignment, the number of possible combinations of chromosomes in a gamete is: 2n (n is number of chromosome types)
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Possible Chromosome Combinations
1 2 3 Possible Chromosome Combinations or or or Figure 10.6 Page 169
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multicelled sporophyte multicelled gametophytes
Plant Life Cycle multicelled sporophyte mitosis zygote Diploid fertilization meiosis Haploid gametes spores multicelled gametophytes mitosis Figure 10.7 Page 170
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Animal Life Cycle Figure 10.7 Page 170 multicelled body mitosis zygote
Diploid fertilization meiosis Haploid gametes Figure 10.7 Page 170
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Oogenesis three polar bodies (haploid) first polar body (haploid)
oogonium (diploid) primary oocyte (diploid) secondary oocyte (haploid) ovum (haploid) Meiosis I, Cytoplasmic Division Meiosis II, Cytoplasmic Division Growth Figure 10.8 Page 171
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Spermatogenesis Figure 10.9 Page 171 spermato- gonium (diploid )
primary spermatocyte (diploid) secondary spermatocytes (haploid) sperm (mature, haploid male gametes) spermatids (haploid) Spermatogenesis Meiosis I, Cytoplasmic Division Meiosis II, Cytoplasmic Division Growth cell differentiation, sperm formation Figure 10.9 Page 171
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Fertilization Male and female gametes unite and nuclei fuse
Fusion of two haploid nuclei produces diploid nucleus in the zygote Which two gametes unite is random Adds to variation among offspring
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Factors Contributing to Variation among Offspring
Crossing over during prophase I Random alignment of chromosomes at metaphase I Random combination of gametes at fertilization
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Mitosis & Meiosis Compared
Functions Asexual reproduction Growth, repair Occurs in somatic cells Produces clones Meiosis Function Sexual reproduction Occurs in germ cells Produces variable offspring
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Prophase vs. Prophase I Prophase (Mitosis) Prophase I (Meiosis)
Homologous pairs do not interact with each other Prophase I (Meiosis) Homologous pairs become zippered together and crossing over occurs
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Anaphase, Anaphase I, and Anaphase II
Anaphase I (Meiosis) Homologous chromosomes separate from each other Anaphase/Anaphase II (Mitosis/Meiosis) Sister chromatids of a chromosome separate from each other
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Results of Mitosis and Meiosis
Two diploid cells produced Each identical to parent Meiosis Four haploid cells produced Differ from parent and one another
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