1. Synthetic Biology Presentation by Brown iGEM Team

2. Building Biotechnology

3. Bacterial Photography

4. E. Coli that smell!

5. Biofuel s GreenFuel Company

6. Invade Cancer Cells 1. Aerobic Conditions 2. Low Oxygen Detected! 3. INVASION!

7. How do we build these?

8. Parts Devices Systems

9. DNA: AATGAATATCCAGATCG

10. Biological Part: Promoter

11. Biological parts are building blocks made of genetic material

12. --- Different Parts connect together Promoter --- Gene Terminato r This is a device

13. MIT Parts Registry A database with standardized genes for easy assembly and reusability.

14. MIT Parts Registry From about 100 parts in 2004 to about 2000 parts in 2007 But still a lot of work to be done!

15. Characterization How does this part work? What does it do?

16. Recap A set of tools and parts to engineer biology

17. What is iGEM? Internationally Genetically Engineered Machines Competition Brown’s Team: 7 undergraduate students

18. Our Projects

20. Lead Sensor Lead contamination is health problem Expensive to sense lead We need cheap solution that doesn’t take long

21. Lead Sensor

22. Tri-Stable Switch

23. Turn on/off three different proteins in cell Differentiation of stem cells Tissue Engineering

24. Synthetic Biology at Brown University Synthetic Biological Systems Professor Wessel Biomechanics Professor Richardson Biomaterials Professor Webster

25. Our Sponsors