1. Motifs of Protein Structure

2. Adapted from “Introduction to Protein Structure” by Branden & Tooze

4.  -helix is a dipole moment. Adapted from “Introduction to Protein Structure” by Branden & Tooze

6. 1 3 2

7. antiparallel  -sheet Adapted from “Introduction to Protein Structure” by Branden & Tooze

9. parallel  -sheet Adapted from “Introduction to Protein Structure” by Branden & Tooze

10. 13425 13245

11. Loop regions are at the surface of protein molecules Adapted from “Introduction to Protein Structure” by Branden & Tooze

12. myoglobin Adapted from “Introduction to Protein Structure” by Branden & Tooze

13. myoglobin triosephosphate isomerase Adapted from “Introduction to Protein Structure” by Branden & Tooze

14. Topology diagram aspartate transcarbamoylase flavodoxin: redox protein plastocyanin: electron carrier Adapted from “Introduction to Protein Structure” by Branden & Tooze

15. helix-turn-helix motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

16. Calcium-binding motif Troponin-C: a muscle protein Adapted from “Introduction to Protein Structure” by Branden & Tooze

17. Calcium-binding motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

18. Conformational change of calmodulin upon peptide binding

19.  -hairpin motif bovine trypsin inhibitor snake venom erabutoxin Adapted from “Introduction to Protein Structure” by Branden & Tooze

20. staphylococcus nuclease Greek key motif Adapted from “Introduction to Protein Structure” by Branden & Tooze

21.  -hairpin motif Greek key motif ? Adapted from “Introduction to Protein Structure” by Branden & Tooze

22.  motif right hand left hand Adapted from “Introduction to Protein Structure” by Branden & Tooze

23. Large polypeptide chains fold into several domains Adapted from “Introduction to Protein Structure” by Branden & Tooze

24. domains are built from structural motifs triosephosphate isomerase Adapted from “Introduction to Protein Structure” by Branden & Tooze

25. protein structure domain motif secondary structure primary structure P53 DNA-binding domain sheet-turn-helix  -helix &  -sheet & turn linear chain

26. simple motifs combine to form complex motifs Adapted from “Introduction to Protein Structure” by Branden & Tooze