1. Antibiotics
Antibiotic

2. Antibiotics - Introduction
Selective toxicity - kills or stops growth of bacteria w/o damaging the host (human body)
Bacteria - unicellular microorganisms - must rely on host for nourishment
Most harmful
Some needed effects
Most bacteria destroyed by immune system

3. Antibiotics - Types
Broad Spectrum - useful on a wide variety of bacteria
Narrow Spectrum - useful on only a few varieties of bacteria

4. Antibiotics - Mechanism of Action
1. Inhibit cell wall synthesis & function
decrease rigidity of cell wall - cause it to burst
Examples
(Penicillin)
(Amoxicillin)
(Cephalosporins, Cephalexin) Keflex
Bacitracin
**high occurrence of allergic reactions

5. Antibiotics - Mechanism of Action
2. Inhibits protein synthesis by attaching to ribosomes
kills bacteria or slows growth
Examples
(Tetracycline)
(Erythromycin)
(Azithromycin) Z-pack, Zithromax

6. Antibiotics - Mechanism of Action
3. Inhibit bacterial DNA/RNA synthesis
affects structure, function, & synthesis of DNA - can’t reproduce
Examples
(Ciproflaxin) Cipro
(Sulfadiazine) Silvadene
(Sulfa)

7. Resistance to Antibiotic Drugs
Bacteria develop natural or acquired resistance to antibiotics - allows bacteria to survive
What can be done????

8. Antiviral
Virus – intracellular parasites, lack cell wall & cell membranes; don’t have metabolic processes
Antiviral medicines treat Influenza A & B and RSV
Examples:
(Famiclor) Famvir
(Zanamivir) Relenza
(Oseltamivir phosphate) Tamiflu