1. Genetic analysis Donald Winslow 25 February 2011 Green peas from Donalds garden

2. Gregor Mendel Illustration from Chapter 3 (Mendelian Genetics) of Klug et al., 2009 Concepts of Genetics, 9 th ed. Pearson/Benjamin Cummings, San Francisco.

3. Objectives Define: heterozygous, homozygous, recessive, dominant, codominant, incomplete dominance, Punnett square, monohybrid cross, dihybrid cross, phenotype, genotype, P generation, F 1 generation, F 2 generation Explain segregation & independent assortment Use Punnett squares to predict results of monohybrid & dihybrid crosses Including human blood group crosses

4. Monohybrid cross Illustration from Chapter 3 (Mendelian Genetics) of Klug et al., 2009 Concepts of Genetics, 9 th ed. Pearson/Benjamin Cummings, San Francisco.

5. Segregation observed Parental (P) Generation: Yellow peas X Green peas First Filial (F 1 ) Generation:Yellow peas Second Filial (F 2 ) Generation:Yellow peas + Green peas

6. Dihybrid cross Illustration from Chapter 3 (Mendelian Genetics) of Klug et al., 2009 Concepts of Genetics, 9 th ed. Pearson/Benjamin Cummings, San Francisco.

7. Autosomal & sex-linked genes Autosomes have homologues Sex linkage Sex determination in Drosophila & humans Heterogametic and homogametic sex

8. Pedigree analysis Male squares, female circles Autosomal recessive disorders Autosomal dominant disorders X-linked recessive disorders PolymorphismPTC tasting