1. Holding slide prior to starting show

2. The Internet is about to byte back! Raising Awareness for e-Science & Grid Computing in Industry & Commerce John Oliver Commercial Coordinator Welsh e-Science Centre

3. Synopsis What is e-Science? What is the Grid & what benefits does it bring? UK e-Science Programme Role of the Welsh e-Science Centre Concluding remarks

4. What is e-Science? e-Science –“science increasingly done through distributed global collaborations enabled by the Internet, using very large data collections, tera-scale computing resources and high performance visualization.”

5. Collaborative Science LARGE HADRON COLLIDER – CERN Typical Data Raw = 1 petabyte/sec Filtered = 100Mbyte/sec = 1 meg CD ROMS per year Physicists collaborating in an international experiment, need to share: Data & storage resources IT resources for: - Information extraction & analysis - Large scale simulation

6. Engineering Design A new aircraft may involve 10,000 engineers from many organisations collaborating, sharing: Digital blueprints & specs Supercomputer simulations Software and data for multidisciplinary simulations

7. Crisis Management SARS GRID – Taiwan May 2003 Medical staff quarantined Short time frame PRAGMA virtual team set up Grid, China, Korea, USA, Australia Access Grid teleconferencing Medical staff sharing expertise, X-rays,patient records,diagnosis data

8. “Post-Genomic” Bioinformatics Biological Databases - larger, more complex & diverse - allows linkage & optimal data exploitation Micro Array experiments - e.g. filtering 30 or 40 results out of 1 million Simulation of large molecules - Protein folding affects how drugs dock with receptors WALES GENE PARK WALES BIOSTATISTICS & BIOINFORMATICS UNIT University of Wales, Departments of: PATHOLOGY PHARMACOLOGY CHEMISTRY

9. Elements in Common COORDINATED PROBLEM SOLVING –Beyond client-server: distributed data analysis, computation, collaboration, –Problem Solving Environments RESOURCE SHARING –Computers, data, instruments, networks “VIRTUAL ORGANISATIONS” –Multi Institutional –Overlying traditional organisational structures –Large or small, static or dynamic

10. The Computing Foundations for e-Science Immersive Visualization Collaborative Tools High Speed Networks &Broadband access High Performance Computing Grid Computing

11. What is the Grid? Lots & lots of resources Secure remote access across adminstrative domains Scalable discovery and seamless composition of diverse resources

12. The Grid Vision Where this power is made available as "services" to users with differing levels of expertise Where "services" interact to perform specified tasks with a minimum of human intervention Imagine a world in which computing power is as readily available as electrical power …..

13. Benefits from the Grid Access to more computing and data resources Lower cost of computing Increased flexibility –to tackle large-scale problems Empowers individuals and organisations –towards better collaboration within and between organisations

14. Some “Healthy” Benefits Bioinformatics Collaborative surgical planning Radiotherapy treatment planning High content imaging in Biosciences Electronic patient records Distributed remote diagnosis

15. science sectorsscience & non-science sectors critical low/zero Importance to business 200020022004200620082010 2012 TODAY i) production grids for research ii) vendors claim “100’s of corporate grid customers” critically important PriceWaterhouseCoopers technology maturity “significant momentum” IBM internal use by large corporates Grid service providers (GSP) 15% of corporates using GSPs Gartner harnessing computer cycles computing as a utility pervasive computing “Great Global Grid” “mature”, real deployments full revolution begins Foster & Kesselman Take-up of Grid Technologies

16. UK e-Science Programme Spending Reviews –2000 : £98m for 3 years (+ £20m from DTI) –2002 : Further £115m for years 4 & 5 Development of key IT infrastructure to support e-Science Managed by Research Councils & DTI –Application specific Pilot Projects –Core programme to identify, develop and deploy generic Grid middleware

17. UK e-Science Network RAL  National Centre in Edinburgh/Glasgow  8 regional centres  Grid support centre Cambridge Newcastle Edinburgh Glasgow Cardiff Southampton Belfast Oxford London Hinxton (EBI) Manchester DL

18. Welsh e-Science Centre School of Computing Funding: - DTI, WDA & CU Role: - Promote e-Science research and development in Wales and South- west of England - Accelerate the adoption of e- Science & Grid capabilities

19. Our Role in Practice Infrastructure Provision Development of technology Outreach to encourage: – e-Science technologies use by researchers –Collaborative research projects –Technology transfer to industry

20. Resources “Monster Computing Power” –Locally: SUN, SGI, storage, visualisation –Resources of the “national grid” ! –Access via Broadband Grid expertise for training and support –Full-time staff (4) –Related Researchers (~20)

21. Welsh e-Science Projects 25+ in progress grouped into Applications Industrial Partnerships Middlewares Tools

22. Project – Biodiversity World Desktop access to analysis tools & diverse data sources to using: Species 2000 ‘Catalogue of Life’ Species geography description & distribution Climate surface & political units Genetic sequences The probability that the climate at any given point is suitable for it to grow Leucaena leucocephala A tropical grazing plant

23. Project - Resource Awareness Visualization Environment To allow several parties to interact with visual data involving different: locations display media bandwidth availabilty in a shared virtual space

24. Project - Triana PSE featuring “pluggable software architecture” allows flexible use as : - workflow management for grid applications - data analysis for signal, image or text processing - application designer tool - “plug-in” your own code  A collection of toolboxes, & a work surface for composition  Drag & Drop” to create workflow

25. Concluding Remarks The vision of the Grid and e-Science is ambitious and far-reaching The Grid is an engine for progress in medicine, healthcare and biosciences driven by a confluence of technologies We are at the start of the Grid era. It’s a long term programme

27. Work done at the WeSC Distributed Visualization Facility (VDF) Translocation modeling of DNA molecules through a membrane pore

28. Visual Molecular Dynamics

29. Computational Steering

30. WeSC Web Site http://www.wesc.ac.uk

31. WeSC Contacts John Oliver Commercial Coordinator Tel: +44(0)29 2087 6998 e-mail: John.Oliver@wesc.ac.uk

32. Thank you for coming