1. Designing nanostructured block copolymer surfaces to control protein adhesion by Scott R. Schricker, Manuel L. B. Palacio, and Bharat Bhushan Philosophical Transactions A Volume 370(1967):2348-2380 May 28, 2012 ©2012 by The Royal Society

2. (a) Structure of the tooth [61] (adapted from www.virtualmedicalcentre.com), and (b) a radiograph showing severe bone loss as a result of periodontal disease (from Rose et al. [82]). Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

3. Progression from a scaffold to tissue (adapted from Baum & Mooney [83]). Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

4. Synthetic scheme for the diblock copolymers [62]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

5. Height and phase images of diblock copolymers compared with their respective homopolymers. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

6. Friction mapping of polymer surfaces [62]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

7. Thermal dependence of the nanostructure. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

8. Height and phase images of the diblock copolymer and respective homopolymers in PBS buffer [62]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

9. Height and phase images of the diblock and triblock copolymer of MMA and AA in PBS [61]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

10. Contact angle of diblock and triblock copolymer [61]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

11. (a) AFM imaging (solid line, height; dashed line, adhesive force) and (b) adhesive force data for BSA adsorption on a PMMA surface [61]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

12. (a) AFM imaging (solid line, height; dashed line, adhesive force) and (b) adhesive force data for BSA adsorption on the block copolymer surfaces [61]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

13. Phase image of the block copolymer coated with BSA [61]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

14. Fibronectin adhesion to PMMA–PAA block copolymer surfaces [107]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

15. Fibronectin adhesion to PMMA–PHEMA surfaces [107]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

16. Schematic illustrating the different polymer–protein interaction modes [107]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

17. Antibody interaction with the RGD group on a polymer surface [111]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

18. Height and adhesive force maps of the interactions between the antibody-functionalized tip and the PMMA–PAA and PMMA–PHEMA block copolymers with no added protein. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

19. Height and adhesive force maps of the interactions between the antibody-functionalized tip and the PMMA–PAA and PMMA–PHEMA block copolymers with added fibronectin. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

20. Height and adhesive force maps of the interactions between the antibody-functionalized tip and the PMMA–PAA and PMMA–PHEMA block copolymers with added BSA. Data for PMMA and PHEMA are taken from the study of Palacio et al. [111]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

21. Phase images taken on the polymer surfaces with added fibronectin, along with the corresponding frequency distribution of the measured phase angle variation for the (a) PMMA– PAA series and (b) PMMA–PHEMA series [111]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

22. XPS survey spectra for the polymer surfaces with fibronectin [119]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

23. High-resolution C 1s, O 1s, N 1s and S 2s XPS spectra for the polymer surfaces with added fibronectin [119]. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society

24. Summary of the major findings on the effect of block copolymer configuration on fibronectin conformation. Scott R. Schricker et al. Phil. Trans. R. Soc. A 2012;370:2348-2380 ©2012 by The Royal Society