1. Presented by Leticia Bonita Prince Newcastle University 4 th Year MChem Student

2. Aims of Today Increase your understanding of carboxylic acids Increase your spatial skills and awareness using software designed by the CCDC

3. What are Spatial Skills? The ability to mentally manipulate 2-dimensional and 3- dimensional figures. Important in chemistry, biology, medicine, mathematics, physics and everyday life.

4. Carboxylic Acids They have the general formula RCOOH (R= H, CH 3, CH 2 CH 3 etc). Good Hydrogen bond DONORS and ACCEPTORS.

5. Nomenclature Look at the R group and add “-oic acid” to it. If there are two carboxylic acid functional groups, you will add –dioic acid to it.

6. Salts Carboxylic acids are more acid than alcohols because their conjugate base is resonance stabilised. This anion can form a salt by bonding ionically with a metal such as sodium.

7. Boiling Points Carboxylic acids have higher boiling points than alcohols. They dimerise through hydrogen bonding creating a bigger molecule which has larger van der Waals’ – more energy to overcome.

8. Solubility In water, the carboxylic acid will form hydrogen bonds with water instead of dimerising which is why some are soluble. HOWEVER, if there is a large alkyl chain (5 carbons +) the carboxylic won’t dissolve due the hydrophobic nature of the R group.

9. Reactions Esters Alcohols Amides Carboxylate Salts Acyl Chlorides Acid Anhydrides

10. Esterification

11. The WebCSD Type in http://webcsd.ccdc.cam.ac.uk/teaching_database_demo.php http://webcsd.ccdc.cam.ac.uk/teaching_database_demo.php Answer the questions by typing the refcodes into the “find entry” box

12. THANK YOU! ENJOY THE REST OF YOUR DAY!