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DNA: The Molecule of Heredity
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DNA Structure Deoxyribonucleic acid.
A macromolecule composed of two strands of monomers called nucleotides. These strands are joined in the middle by hydrogen bonds. The strands twist around one another forming a double helix.
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Nucleotide Structure 5-C sugar – deoxyribose Phosphate group
Nitrogen containing base -4 of two types Adenine Guanine Cytosine Thymine
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Types of Nitrogen Bases
Purines – have two rings in their structure Adenine Guanine Pyrimidines – have one ring in their structure Thymine Cytosine
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Nitrogen Base Pairing Bases pair in a specific pattern.
A purine always bonds to a pyrimidine Adenine bonds to thymine. Guanine bonds to cytosine.
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Nitrogen Base Pairing The bases are held together by weak hydrogen bonds. The sides of the DNA ladder are composed of alternating sugar and phosphate and are called “backbones”.
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Discovery of DNA Structure
This structure was discovered by the work of James Watson and Francis Crick. These two scientists viewed x-ray images of DNA crystals that were created by Rosalind Franklin and Maurice Wilkins.
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Functions of DNA DNA is the molecule of heredity.
- It provides instructions for cell functions and is a blueprint for the production of proteins that do the work of the cell. DNA must be able to copy itself exactly. - This process is called replication Enzymes control the process.
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Replication – Overview
· DNA “unzips” down its H-bonds · One strand then acts as a template for the production of a new strand · Each new DNA molecule has one old strand of nucleotides and one new strand.
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Control Of Cell Activities
DNA is copied into RNA. (transcription) RNA in turn controls the production of proteins. (translation) Proteins then do the work of the cell.
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