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TILDA and the HRB Professor Rose Anne Kenny Trinity College Mercers Institute St James Hospital
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T he I rish L ongitu D inal study on A geing TILDA
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Trinity College Dublin, The University of Dublin Trinity EngAGE Centre for Research in Ageing International Impact (2009-2013) Geriatrics & Gerontology: % of Papers in Top 1% - International Source/s: InCites/Web of Science/Scopus
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Trinity College Dublin, The University of Dublin InnoLife Consortium- Health and Ageing European Institute of Technology KIC EIT Budget €2.7B (2015- 2020) TCD Imperial Oxford Cambridge Newcastle Karlinski
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Research Policy Practice www.tilda.ie
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New knowledge Population research Clinical trials Policy needs Policy impact Training www.tilda.ie
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8,504 Participants 50+ www.tilda.ie
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Every 2 years For 10 years 2010, 2012, 2014, 2016..... www.tilda.ie
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Creating Infrastructure Biobanking, Population sample, Multidisciplinary- HUB Training Education –community Soft ware 2010, 2012, 2014, 2016. refresh.... www.tilda.ie
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Health Wealth Happiness www.tilda.ie
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GenesGenesNutritionNutrition FamilynetworksFamilynetworks SocialparticipationSocialparticipation EducationEducation HouseholdStructureHouseholdStructureMaritalStatusMaritalStatus Work & Retirement Retirement Income & assets Income HealthHealth Experience of Ageing Experience MentalhealthMentalhealth www.tilda.ie
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TILDA Data Wave 1 Wave 2 Health 2593 2757 Social 898 1725 Economic867 978
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2014 HRA: Inequalities in Access to GP Care in Ireland: An Analysis using Longitudinal Data €329,988 (€150,424 to TILDA) HRA: Hypotension, vasoreactivity and white matter intensities in the ageing brain: The Irish Longitudinal Study on Ageing (TILDA) - €330,000 HPF Research Training Fellowships for Healthcare Professionals (2014) - €244,206 2013 HRA: Targeted actions to identify novel inflammatory and immunological factors associated with predisposition to AMD in the TILDA population cohort (2013) [Overall budget €329,987] 2012 HRB ICE: Interdisciplinary Capacity Enhancement (ICE) Awards 2012- Effecting change in cardiovascular health in older Irish Adults (2012) - €589,327 HRA: Project SADD: Socioeconomic position, anxiety, depression and diabetes in the ageing population in Ireland (2012)- €331,000 2011 HRB ICE: Interdisciplinary Capacity Enhancement (ICE) Awards 2011- Building research and implementation capacity in the Irish Longitudinal Study on Ageing (TILDA): health inequalities, mental health and opportunities to influence health and social care policies - €794,681 HRA: Frailty and Cognitive impairment in the older population (2011) - €297,750
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HRB PhD Scholars programme 6 Ph.D. Scholars (2008-2010 ) 15 Ph.D. Scholars 2010- TILDA Core – 10 Ph.D 2009- 2013 4 Ph.D. present
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The Active Stand
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Heart Rate Recovery and Mortality
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Slow Heart Rate Recovery and Mortality
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(Finucane C et al Circulation 2015) Orthostatic cardiovascular responses to standing SBPDBP
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Poorer People Have A Higher Resting Heart Rate
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Social Networks are Beneficial for Health J Geront Series B 2014
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Hypertension prevalence over 50 years (TILDA wave 1). Awareness in hypertensives Blood pressure controlled to SBP<140 mmHg and DBP<90mmHg52% Treatment in hypertensivesBP control in the treated On antihypertensive medication (ATC codes CO2, CO3, CO7, CO8, CO9)59% Awareness defined as a self-report of ever having a doctor’s diagnosis of hypertension55% 64% 64% of those aged 50yrs and older were hypertensive
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Statin use in groups at high risk of CVD (50-64 years, W1) Statin use for secondary prevention (those with existing CVD) is lower than expected given the strength of evidence for the use of statins in this group –known CVD 68.8% using statins –multiple CVD events 78.6% using statins.
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Statin use in groups at high risk of CVD (50-64 years, W1) Statin use for secondary prevention (those with existing CVD) is lower than expected given the strength of evidence for the use of statins in this group –known CVD 68.8% using statins –multiple CVD events 78.6% using statins Statin use for primary prevention in those at high risk of CVD is also low –Known diabetics 57.4% using statins –High or very high absolute risk group 19.0% using statins.
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Childhood Adversity Increases Risk of Psychiatric Disorders in Later Life
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Risk of Disease Increases as the Number of Adverse Childhood Events Increases
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Project SADD: Socioeconomic position, anxiety, depression and diabetes in the ageing population −Diabetes affects 8.3% of adults aged 50+ in Ireland, rising to 12% in those aged 75+ −primary level or no education are 60% more likely to have diagnosed diabetes −Cross-sectionally, diabetes is not independently associated with depression or anxiety −those with diagnosed diabetes at Wave 1 reported a Major Depressive Disorder (11.9% vs. 7.4%) or Generalized Anxiety Disorder (12.8% vs. 7.5%) after a two year follow-up
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