1. On-chip Microperistaltic Pump D. Michael Ackermann, Jon Payne, Hilary Samples, James Wells

2. Goals Redefined Cell Culture Cell Culture Filtering Filtering Pump Pump View/Data Acquisition View/Data Acquisition Pump Pump

3. The Problem: Get onboard! Additional bulky equipment needed Additional bulky equipment needed Difficult setup Difficult setup Not appropriate for commercial applications Not appropriate for commercial applications

4. Current Proposed Design Goal Drive peristalsis on- chip – use PZT? Drive peristalsis on- chip – use PZT? Have all necessary electronics onboard Have all necessary electronics onboard Reprogrammable MCU? Reprogrammable MCU? Labview Interface or other? Labview Interface or other? http://www.wtec.org/loyola/mcc/mems_eu/Pages/Chapter-5.html

5. Progress: MicroPump Researching Pump Designs Researching Pump Designs Exploring PZT options Exploring PZT options Dr. Goldfarb Dr. Goldfarb In contact with 2 PZT companies In contact with 2 PZT companies –Kinetic Ceramics –Face Co. “Thunder” www.g-e-m.com/products/ termination.html

6. Progress: MicroSieve 20 um Beads 20 um Beads Problems with manufacturing Problems with manufacturing Stop cells – allow for culture Stop cells – allow for culture

7. Progress: Overall Design DesignSafe DesignSafe Project Redefined! Project Redefined! DesignerOperator Franz ! !

8. Future Work Determine if PZT is workable option Determine if PZT is workable option Look into other potential drivers Look into other potential drivers Explore fabrication options Explore fabrication options Redo Innovation Workbench Redo Innovation Workbench

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