1. Scientific coordinator: Dr. Garbovan Cristina Author : Petroi Raluca Coauthor: Pocol Oana

2. Introduction The clinical conseqence of progressive infection with HIV is the development of opportunistic infection as a rsult of progressive loss of immune function. Although there are many potential pathogens can complicate AISD, only a very limited number can cause meningitis.

3. Material and method We have made a retrospective study on 14 patients who were admitted in Disseas Clinic I from Tirgu Mures between 01.01.2012-31.12.2013. the studied criteria were etiology, clinical parameters like LCR, ionogram, hemoleucogram and treatment of meningitis.

4. Etiology Different forms of meningitis are associated with HIV infection. They may be classified as follows, according to the etiologic agent: -cryptococcal -tuberculous -listeria species -toxoplasmosis

5. In Tirgu Mures the etiology of this patients is :

6. Clinical presentation In general, symptoms and signs typically associated with meningitis are less likely to occur in HIV-seropositive individuals than in the general population. This probably reflects the different organisms involved and the differences in immune responses. Less frequent findings are confusion,somnolence and personality changes.

7. Distribution of patients by associated pathology

8. Distribution of patients by the changes of leukocytes

9. Distribution of patients by the changes of hemoglobin

10. Distribution of patients by the changes of potasium

11. Distribution of patients by the changes of sodium

12. Distribution of patients by the aspect of the LCR

13. Distribution of patients by Pandy reaction

14. Distribution of patients by the changes of glucoses in LCR

15. Distribution of patients by the changes of proteine in LCR

16. Meningitis in patients with HIV disease is most frequently due to opportunistic infections. Thus, predictions center on the likelihood of controlling opportunistic infection. The best way to prevent opportunistic infections is to give effective antiretroviral therapy - the future epidemiology of opportunistic infections is inextricably linked with the effectiveness of future antiretroviral treatment Coclusions