1. Daily Entry 1. A specialized cell that functions in sending chemical and electrical signals is? 2. A living plant specialized cell that transports sugar? 3. Blood cells with nuclei are referred to as? 4. A specialized cell that has a lot of mitochondria and a flagellum for movement? 5. An unspecialized cell?

2. Stem Cells

3. Video (Both links are to the same video, try the other if one doesn’t work) http://www.eurostemcell.org/films/a-stem- cell-story/English http://www.eurostemcell.org/films/a-stem- cell-story/English http://www.youtube.com/watch?v=2-3J6JGN- _Y http://www.youtube.com/watch?v=2-3J6JGN- _Y

4. Introducing stem cells

5. Stem cell biology basics

6. A life story…

7. What is a stem cell? Identical stem cells Stem cell SELF-RENEWAL (copying) Stem cell Specialized cells DIFFERENTIATION (specializing) Stem cell= an undifferentiated cell that has not been given a specific job or function yet, once it is given a specific job it is then differentiated/specialized

8. 1 stem cell Self renewal - maintains the stem cell pool 4 specialized cells Differentiation - replaces dead or damaged cells throughout your life Why self-renew AND differentiate? 1 stem cell

9. Where are stem cells found? 1. embryonic stem cells blastocyst - a very early embryo 2. tissue stem cells fetus, baby and throughout life

10. Types of stem cell: 1) Embryonic stem cells

11. Embryonic stem (ES) cells: Where we find them embryonic stem cells taken from the inner cell mass culture in the lab to grow more cells fluid with nutrients

12. Embryonic stem (ES) cells: What they can do embryonic stem cells PLURIPOTENT- capable of developing into any type of cell, these are very important to research all possible types of specialized cells differentiation

13. neurons grow under conditions B Embryonic stem (ES) cells: Challenges embryonic stem cells skin grow under conditions A blood grow under conditions C liver grow under conditions D ?

15. Types of stem cell: 2) Tissue stem cells

16. Tissue stem cells: Where we find them muscles skin surface of the eye brain breast intestines (gut) bone marrow testicles

17. Tissue stem cells: What they can do MULTIPOTENT-can give rise to other types of cells but it is limited in its ability to differentiate Ex:Bone marrow also contains multipotent stem cells that give rise to all blood cell types but not any other type of specialized cells blood stem cell found in bone marrow differentiation only specialized types of blood cell: red blood cells, white blood cells, platelets

19. Pros vs. Cons Transplant organs Discovery of new medicine/drugs Cure for diseases – Cancer Skin grafts Genetic disorders Injuries and healing – Spinal Cloning Ethical/emotional issues – abortion Religious beliefs Fear of cloning Against human experimentation Long term side affects are unknown and still in progress Multipotent Expensive

20. HOW COULD STEM CELL RESEARCH BENEFIT OTHER COUNTRIES? Think Globally

21. Think-Pair-Share Think: President Obama recently overturned a ban on federal funds for stem cell research. Should stem cell research be federally funded? Are you for or against stem cell research? Pair: Turn to your neighbor and share your thoughts

22. Left-side Activity Create a public announcement, newspaper article, flyer, advertisement, t-shirt design ect. Representing your opinion on stem cell research Include – What a stem cell is – The two types of stem cells – Where stem cells come from – How they can be used – Illustration