1. The French National Alliance for Life Sciences and Health AVIESAN Prof. André Syrota Chairman and CEO of Inserm President of Aviesan STOA, Brussels, June 2012 1

2. The scientific and political context - Changes in the French research and higher education landscape. 2007: The autonomy of the universities. 2009: University Hospitals become research operators. 2011: Investments for the future : 35 billion (2.5 billion for life and health sciences – equipments, cohorts, infrastructures, university hospital institutes, technological research institutes,…) - The scientific challenges of the 21 st century. Biology becoming « an integrative science ». New Health challenges: personalised medicine, ageing, emerging and reemerging diseases, health care systems,… - A complex organisation in Health and Life sciences

3. The French National Alliance for Life and Health Sciences (Aviesan) 3

4. 4 Aviesan main objectives Scientific coordination Strategic analysis Scientific foresight Programming (National and European levels) Operational coordination Partnership with universities (funding, human resources) Transfer of knowledge Simplification More visibility and reactivity To share priorities on structuring projects

5. 5 Aviesan 10 multi-organization thematic institutes (Itmos) Molecular and structural bases of living organisms Cell biology, development and evolution Genetics, genomics and bioinformatics Immunology, hematology, and pneumology Microbiology and infectious diseases ANRS Public health Health Technologies Neurosciences, cognitive sciences, neurology and psychiatry Alzheimer Cancer INCa Circulation, metabolism, and nutrition

6. 6 Aviesan: Achievements Strategic analysis & scientific foresight Scientific animation Annual conferences, thematic workshops and working groups (H1N1, Nutrition and Cancer, Vaccines, Radiobiology, Environment and Cancer, Epigenetics, Bioinformatics, rare diseases, etc ) Programming National Research Agency (ANR), Thematic agencies within Aviesan Itmos, Investments for the future: research infrastructures European level: JPI, ESFRI BMS, FP7 Health priority, H 2020 Structuring actions H1N1, Research infrastructures, Environment and Health,Synthetic Biology Partnership with Universities Transfer of knowledge

7. 7 Aviesan: Transfer of Knowledge - Annual meeting at the Governmental level Neurosciences, Metabolism and Cardiovascular, Infectious diseases R&D dating - Sanofi Aventis-Aviesan agreement Sponsorship Collaboration agreements Joint funding for project maturation - Covalliance - The epidemiologic portal Strategic Council for health industry: Aviesan as the most appropriate partner

8. Thank you for your attention 8