1. 1 Cataract Surgery Stephen G. Slade MD, FACS

2. 2 Financial Disclosure Alcon, AMO, B&L Consultant, Clarity, NuLens, RVO, Technolas 2 This presentation represents the speaker’s professional experience.

3. 3 18,900,000 Global Procedures 201018,900,000 Global Procedures 2010 3,261,000 US Procedures3,261,000 US Procedures 900 million US Equipment and Packs900 million US Equipment and Packs 85 million US Presbyopes85 million US Presbyopes 72% with 0.5 D or greater Astigmatism72% with 0.5 D or greater Astigmatism US Cataract Market Medicare, Marketscope

4. 4 US Eye Surgeons Cataract Only Surgeons 4,990 Refractive Only 1,350 Cataract / Refractive Surgeons 2,260 Total 8,600 Marketscope Surveys

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6. 6 Is Cataract Surgery Effective Enough? 20/40 or better 20/40 or better 20/20 or better 20/20 or better 20/40 and J3 or better 20/40 and J3 or better 20/25 and J1 or better 20/25 and J1 or better 75% 100% 85% 35% * Adapted from FDA clinical data for Crystalens and Wavelight Trials Wavelight FDA Trial, Myopia Astigmatism. Crystalens AT 45 FDA Only 6.4% penetration rate Visual Outcomes less than LASIK No safety improvement Surgeon confidence lower Only 6.4% penetration rate Visual Outcomes less than LASIK No safety improvement Surgeon confidence lower

7. 7 Medicare vs Private Pay 7 Source: 2007 Medicare Data 66% Medicare 22% Non Medicare 12% Medicare Managed Care

8. 8 US Surgeries by Ownership Physician Owned ASC 60.6% Corporate Owned ASC 17.1% Hospital Owned ASC 22.3% Source MarketScope

9. 9 Cataract Surgeons by Volume 200-599 47.2% 600-1199 17.9% 1200-1599 2.6% >1600 1.5% <100 13.3% 100-199 17.5% Source MarketScope

10. 10 What percentage of your eligible patients elected to receive premium IOLs in the past 3 months? A. 0% to 10% B. 11% to 20% C. 21% to 30% D. Greater than 30% Question #1

11. 11 What premium lens is your lens of choice for your patients? A. Crystalens 5.0 B. Crystalens HD C. Crystalens AO D. Acrysof ReSTOR IOL (+3.0D) E. Tecnis MF F. AcrySof Toric G. Other H. None, I prefer monofocal IOLs Question #2

12. 12 What is the most important distance to be on target for in the Premium Channel? A. Distance B. Intermediate C. Near Question #3

13. 13 If it was your own eye, which lens would you select? A. AcrySof Toric IOL B. Tecnis Multifocal IOL C. Crystalens 5.0 D. Crystalens HD E. Crystalens AO F. AcrySof ReSTOR IOL (+3.0) Question #4