1. November 8, 2005JLAB Awake Animal Project New Instrumentation for JLAB Awake Animal Project Smaller Pixel Size requires higher granularity in PMT (2.4 – 1.2 mm) Higher granularity requires more anodes More anodes require more resistive network and/or more acquisition channels Need optimal readout electronics and data acquisition system

2. November 8, 2005JLAB Awake Animal Project Two Options for Readout Electronics of 10 cm X 20 cm Gamma-Camera B CD A Resistive Network with 4 Output Channels per Module 4 Output Channels X 8 Modules = 32 Channels Total 8 Rows and 8 Columns with 16 Output Channels 32 Output Channels X 2 Modules = 64 Channels total Each Module Read Out Separately 2x2 Modules Read Out in Series Type I Type II

3. November 8, 2005JLAB Awake Animal Project Raw Image showing four Hamamatsu 8500 tubes (each tube 5 cm square) Raw Image Summed in Y-Dimenision Showing High-Contrast and Spatial Uniformity 10 cm X 10 cm Gamma-Camera Built for Deutsches Krebsforschungszentrum (German Cancer Research Center) Gamma Camera Components

4. November 8, 2005JLAB Awake Animal Project Dual Modality Gamma/Optical Imager Deutsches Krebsforschungszentrum (German Cancer Research Center) Gamma/Optical System on Tomographic Gantry Tc-99m MDP Bone Scan Planar, Pinhole Collimator

5. November 8, 2005JLAB Awake Animal Project New 10 cm X 20 cm Gamma-Camera for John Hopkins University Awake Animal Imager Composed of Two Modules Like the 10 cm X 10 cm Gamma-Camera Made for the Deutsches Krebsforschungszentrum

6. November 8, 2005JLAB Awake Animal Project New 10 cm X 20 cm Gamma-Camera for John Hopkins University Awake Animal Imager Image Showing Two Modules of 4 Tubes Close-Up of Central Region Showing Pixel Resolution in Crack Between Tubes of Different Modules Module 2 Module 1

7. November 8, 2005JLAB Awake Animal Project Resistive Network with Four Readout Channels 1.2 mm step CsI(Tl) crystal with 22 Na source Resistive Network used to read out 1024 channels of Burle 85021 PMT using four readout channels Lineout of Image Showing High-Contrast Pixel Separation

8. November 8, 2005JLAB Awake Animal Project Readout Data Acquisition System PCI Based System –Two 16 channel Datel PCI416 cards in the current two detector / 16 channel per detector system –Two 32 Channel Datel PCI417 needed for next 64 channel detector (type 2) –One 32 Channel Datel PCI417 needed for next 32 channel detector (type 1) VME Based System –Capable of modules of 64 channels USB Based System –Capable of modules of 128 channels