1. Submitted by Roger French Affiliation Case Western Reserve Manipulating Long Range Interactions in Mesoscale Systems Opportunity (WHY?) Impact (SO WHAT?) Timeliness (WHY NOW?) Why now and not earlier? Computation of vdW interactions are now tractable Now able to study combined vdW & ES at the level of charge densities Heterogenous materials systems, including inorganic and biomolecular of increasing importants for assembly As we develop an integrated understanding of LRIs In real heterogeneous systems We can control mesoscale assembly & disassembly stability and destabilization dynamics and temporal evolution Of functional energy materials Approaches (HOW?) Data from Vacuum ultraviolet spectroscopy ab initio optical properties of large molecules LRI computations for complex, anisotropic configurations Combined vdW & ES interactions from Light scattering, osmostic stress SAXS, Nuetron scattering, Advances in determining the van der Waals (vdW) and Electrostatic (monopolar and multipolar) long range interactions in heterogeneous materials systems enable control of mesoscale assemblies. The role of thermal fluctuations and disorder in vdW/Casimir interactions is well recognized How these fluctuations couple to the conformational, electrostatic and polar interactions in these systems is critical to understand de/stabilization and dynamics. These enable understanding the temporal evolution of our mesoscale assemblies. French, R., Parsegian, V., Podgornik, et al., 2010. Long range interactions in nanoscale science. Reviews of Modern Physics 82, 1887, doi:10.1103/RevModPhys.82.1887

2. For optically and morphologically anisotropic systems experimental & ab initio optical properties Fully retarded vdW interactions and Hamaker Coeffs. Forces, Torques and Free Energies of Interactions Retarded vdW Interactions in anisotropic systems Rajter, R.F., French, R.H., Ching, W.Y., Podgornik, R., Parsegian, V.A., 2012. RSC Adv. doi:10.1039/C2RA20083J

3. Partial Charge Distribution in RGD Peptide RGD Peptide Partial Charge Redistribution Polar interactions How do these fluctuate with solvent charge dynamics Bring LRIs onto a common, integrated basis Adhikari, P., Wen, A.M., French, R.H., Parsegian, V.A., Steinmetz, N.F., Podgornik, R., Ching, W.-Y., 2014 Sci. Rep. 4. doi:10.1038/srep05605