1. August 20, 2003 Focus Area 14: Immunization and Infectious Diseases Progress Review

2. Immunization and Infectious Disease Objectives Immunization objectives 14-23Vaccination in day care, grades K and 1 14-24Fully immunized children Plus others on Disease prevalence Children and vaccination Provider practice Immunization registries High-risk adults Adverse events Vaccine safety

3. Immunization and Infectious Disease Objectives Infectious Disease objectives 14-10Identification of persons with chronic Hepatitis C. 14-15Prevention services for International travelers. Plus others on Hepatitis A, B, and C Bacterial meningitis Peptic ulcer hospitalizations Pneumococcal infections Antibiotics use Meningococcal disease Hospital-acquired infections Lyme disease Anti-microbial use in ICU’s Group B streptococcal disease.

4. Immunization and Infectious Disease Objectives Tuberculosis objectives Tuberculosis Curative therapy for tuberculosis Treatment for high-risk persons Timely laboratory confirmation

5. Morbidity Profile Disease Average prevalence 20 th Cent. cases 2000 cases Target Measles503,282370 Diphtheria175,88510 Mumps152,2092380 Pertussis147,2718,2962,000 Rubella47,745140 H. Influenzae, type b 20,0001670 Polio (paralytic)16,31600 Tetanus1,314220 Congenital Rubella Syndrome82330

6. DTP(3+) MMR(1+) Polio (3+) Hib (3+) Hep B (3+) Varicella (1+) Note: Children in the USIS and NHIS were 24-35 months of age. Children in the NIS were 19-35 months of age. Source: USIS (1967-1985), CDC, Division of Immunization, NHIS (1991-1993) CDC, NCHS, and NIS (1994-December 2002), CDC, NIP and NCHS; No data from 1986-1990 due to cancellation of USIS because of budget reductions 2010 Target Vaccine-specific coverage rates among pre-school aged children Percent

7. White, Not Hispanic Black, Not Hispanic Hispanic American Indian / Alaskan Native Asian Universally Recommended Vaccination Coverage Among Children 19-35 Months, 2002 I 95% Confidence interval. § Data are statistically unreliable. Source: NIS, CDC, NIP and NCHS. Percent 2010 Target Native Hawaiian/ Other Pacific Islander Multiple Race Obj. 14-22 § § §

8. White, Not Hispanic Black, Not Hispanic Hispanic American Indian / Alaskan Native Asian ‡ Developmental objective. Target has not been determined. I 95% Confidence interval. § Data are statistically unreliable. Source: NIS, CDC, NIP and NCHS. Universally Recommended Vaccination Coverage Among Children 19-35 Months, 2002 DTP (4+) DTP (3+) Percent 4:3:1:3:3 Series 2010 Target PCV(3+) ‡ Percent Native Hawaiian/ Other Pacific Islander Multiple Race Obj. 14-22 § § § § § § (2001) (2002)

9. Note: Percent receiving vaccine is estimated per Influenza season, using the January-June interviews only. Source: NHIS, CDC, NCHS. 2010 Target Influenza Vaccination Coverage During the Past 12 Months, Among Adults 65 Years and Older Percent 1988 1990199219941996 19982000 Obj. 14-29a 2002

10. † Data are preliminary. Source: NHIS, CDC, NCHS. White African American Hispanic 2010 Target Asian Total Pneumococcal Vaccination Coverage Ever Received Among Adults 65 Years and Older Percent Obj. 14-29b †

11. Hepatitis A Incidence 1999 ACIP recommendations 1996 ACIP recommendations 1995 vaccine licensure † 2002 Data are preliminary. Source: NNDSS, CDC, EPO. Cases per 100,000 19801985199019952000 2010 Target Obj. 14-6 2002

12. Hepatitis A Incidence 1999 ACIP recommendations 1996 ACIP recommendations 1995 vaccine licensure † 2002 Data are preliminary. Source: NNDSS, CDC, EPO. Cases per 100,000 19801985199019952000 2010 Target Obj. 14-6 2002 19 years and older Less than 19 years old

13. Hepatitis B Incidence Source: NNDSS, CDC, EPO. Estimated cases per 100,000 19-39 years 40 years and older Less than19 years Obj. 14-3 19902002 20001998199619941992 1991 ACIP recommendations (for infant vaccination schedule)

14. Hepatitis B Incidence Source: NNDSS, CDC, EPO. Estimated cases per 100,000 (log-scale) 19-39 years 40 years and older Less than19 years Obj. 14-3 19902002 20001998199619941992

15. Hepatitis B Incidence, 2001 American Indian/ Alaska Native I 95% Confidence interval. Source: NNDSS, CDC, EPO. Per 100,000 2010 target 19-24 years 25-39 years 40 years and older Asian or Pacific Islander Hispanic White, Not Hispanic Black, Not Hispanic Obj. 14-3

16. 2010 target Rates of Tuberculosis Note: Data in parentheses represent the percent change in the rates between 1998 and 2001 Source: NTBSS, CDC, NCHSTP. 20011998 American Indian or Alaska Native Asian or Pacific Islander Black, Not Hispanic White, Not Hispanic Hispanic TOTAL Obj. 14-11 Per 100,000 population (-15%) (-11%) (-12%) (-13%) (-20%) (-26%)

17. Percent 2010 target Proportion of Tuberculosis Patients Completing Curative Therapy Source: NTBSS, CDC, NCHSTP. 19991996 American Indian or Alaska Native Asian or Pacific Islander Black, Not Hispanic White, Not Hispanic Hispanic TOTAL Obj. 14-12

18. Progress Review data and slides can be found on the web at: http://www.cdc.gov/nchs/hphome.htm