1. MALARIA AND NEGLECTED TROPICAL DISEASES (NTDs): FINDINGS FROM THE 2012 G-FINDER REPORT

2. Policy Cures Innovative ideas and accurate analysis to accelerate development and uptake of new drugs, vaccines, diagnostics and other products for neglected diseases of the developing world

3. Annual survey of global investment into R&D of new neglected disease products Neutral, comparable, comprehensive analysis Commissioned by the Bill & Melinda Gates Foundation 31 neglected diseases 134 product areas All R&D stages G-FINDER

4. $84.9m higher in 2011 than in 2007 Malaria – overall funding

5. Malaria – by product area Vaccines, diagnostics and vector control R&D ↑ Drug R&D → Basic research ↑

6. Who funds malaria R&D? Gates Foundation 26.3% US NIH 20.7% Industry (aggregate) 18.7% 66%

7. NTDs 50% 65% Buruli ulcer Dengue Kinetoplastids (Chagas, HAT, leishmaniasis) Helminths (lymphatic filariasis, STHs, cysticercosis, onchocerciasis, schistosomiasis) Leprosy Trachoma HIV/AIDS Malaria TB Diarrhoeal diseases Bacterial pneumonia & meningitis Salmonella infections Rheumatic fever Guinea worm disease Echinococcosis Foodborne trematode infections Rabies Yaws WHO classificationG-FINDER

8. NTDs – dengue, kinetoplastids and helminths

9. NTDs – leprosy, Buruli ulcer and trachoma $7.4m$5.8m $9.6m

10. Download the full report at www.policycures.org/g-finder2012.html