1. Chapter 13. Therapeutic and Prosthetic Devices Michael R. Neuman Medical Instrumentation Application and Design, 4th Edition John G. Webster, Univ. of Wisconsin, Madison ISBN: 978-0-471-67600-3

2. Figure 13.1 Block diagram of an asynchronous cardiac pacemaker

3. Figure 13.2 Unipolar and bipolar implementations of both J-shaped and nonpreshaped leads. All models have distal cathode. Bipolar designs typically have a ring anode proximal 10–15 mm on the lead. From J. G. Webster, Ed., Design of cardiac pacemakers, New York, IEEE Press, 1995.

4. Figure 13.3 A demand-type synchronous pacemaker Electrodes serve as a means of both applying the stimulus pulse and detecting the electric signal from spontaneously occurring ventricular contractions that are used to inhibit the pacemaker's timing circuit.

5. Figure 13.4 An atrial-synchronous cardiac pacemaker, which detects electric signals corres­ponding to the contraction of the atria and uses appropriate delays to activate a stimulus pulse to the ventricles.

6. fig_13_05 Figure 13.5 (a) The signal from an acceleration sensor within the rate- responsive pacemaker is bandpass filtered to minimize noise, then rectified and low-pass filtered to yield the activity estimate. (b) The physician selects a programmable curve that has a more sensitive acceleration/pacing rate relationship during low and high levels of activity, with a less sensitive intermediate slope to maintain stability during ordinary workloads. From J. G. Webster, Ed., Design of cardiac pacemakers, New York, IEEE Press, 1995.

7. Table 13.1

8. Figure 13.6 Examples of early pacemakers (top row) and metal encapsulated devices (bottom row). The two units on the bottom right are modern pacemakers that are about the size and mass of a pocket watch. Photograph courtesy of Medtronic Corp.

9. Figure 13.7 A transcutaneous RF-powered electric stimulator Note that the implanted circuit of this stimulator is entirely passive and that the amplitude of the pulse supplied to the electrodes is dependent on the coupling coefficient between the internal and external coils.

10. fig_13_08 Figure 13.8 A stimulator system for use on stroke patients suffering from gait problems associated with dropfoot.

11. Figure 13.9 Block diagram of a cochlear prosthesis

12. Figure 13.10 The square and trapezoidal waveform defibrillator may have a battery that drives the ac charging supply. Diode D rectifies the ac to charge capacitor C. Series SCR1 is turned on to deliver current to subject RL. The timing circuit calculates the charge delivered, then after duration d, shunt SCR2 short circuits the charge. (From L. A. Geddes, Cardiovascular Devices and their Applications, New York: John Wiley & Sons, 1984.)

13. fig_13_11 Figure 13.11 An automatic external defibrillator (AED) visually and vocally instructs the operator to place the conductive adhesive polymer electrodes on the upper and lower chest. It measures the electrocardiogram and if it detects ventricular fibrillation it instructs the operator to press the shock button.

14. Figure.13.12 In a cardioverter, the defibrillation pulse must be synchronized with the R wave of the ECG so that it is applied to a patient shortly after the occurrence of the R wave.

15. fig_13_13 Figure 13.13 Connection of a pump oxygenator to bypass the heart. A disk- type oxygenator is used with a roller pump. Venous blood is taken from a cannula in the right atrium, and oxygenated blood is returned through a cannula in the femoral artery.

16. Figure 13.14 An artificial kidney The dialysate delivery system in this unit mixes dialysate from a concentrate before pumping it through the exchange chamber.

17. fig_13_15 Figure 13.15 In extracorporeal shock-wave lithotripsy, a biplane x-ray apparatus is used to make sure the stone is at the focal point of spark- generated shock waves from the ellipsoidal reflector.

18. Figure 13.16 A continuous-positive-airway-pressure (CPAP) apparatus blows air through the nose to prevent airway collapse during sleep. During expiration, the pressure sensor senses the increased pressure and raises the arrow-shaped occluder to make expiration easier.

19. Figure 13.17 Block diagram of a proportional temperature controller used to maintain the temperature of air inside an infant incubator.

20. Figure 13.18 Block diagram of the electronic control system for a fluid or drug delivery pump

21. Figure 13.19 A block diagram of an implantable artificial pancreas showing the major components of the system.

22. Figure 13.20 (a) Block diagram for an electrosurgical unit. High- power, high-frequency oscillating currents are generated and coupled to electrodes to incise and coagulate tissue, (b) Three different electric voltage waveforms available at the output of electrosurgical units for carrying out different functions.

23. Figure 13.21 Block diagram of a typical electrosurgical unit

24. Cardiac ablation electric current from the catheter tip electrode heats cardiac tissue to destroy it