1. Cellular biology-Why do we need to know this?

2. Bushong

3. When an atom is ionized zChemical binding properties change zin large molecules: breakage or relocation of molecules…become abnormal zAbnormal means zFunction improperly zcease to function -impairment or death of cell

4. Damage is Reversible zIonized atoms become neutral…How? zMolecules are mended by repair enzymes zImmediate response to radiation zLatent response z(Bushong) see Box 32-1

5. RADIATION INTERACTS AT ATOMIC LEVEL zAtoms combine to form molecules zThe body is made of macromolecules zWhat is the definition of macromolecules?

6. With this kind of potential damage…. The government tends to get involved CHAPTER 9 SHERER

7. YOU ARE RESPONSIBLE FOR DIFFERENTIATING BETWEEN zICRP zNCRP zUNSCEAR zNAS/NRC-BEIR zNRC zEPA zFDA zOSHA

8. What is the smallest element of protoplasm? zThe cell zWhich of the following macromolecules contain enzymes for repair? A) proteinb) lipids c) carbsd) nucleic acids z

9. MORE QUESTIONS z_____provides most of the cell’s energy zDNA and RNA are two types of these zWhat is function of lipids z Carbohydrates z Nucleic acids z store energy z component of membrane z protects against cold and heat z assists in digestive process z components of substances such as hormones

10. zTissues are groups of ? zOrgans are groups of ? zSystem is a group of? zAn organism is? z Cells z tissues z organs z a human

11. CELLULAR ANATOMY zRibosomes zMitochondria zEndoplasmic Reticulum zLysosomes zGolgi Apparatus

12. RADIATION BIOLOGY CHAPTER 6..an introduction-What do you already know?

13. DO YOU REMEMBER BERGONIE AND TRIBONDEAU? Pg 102 (Sherer)

14. TWO TYPES OF CELLS zSomatic zGerm

15. MALIGNANT CELLS zDivide abnormally zincreased amount of chromatin zincreased amount of nuclear material znormal cells stay together (tissue) zsome malignant cells break away to other tissues

16. Direct effect zWhere do you think the radiation hits to be given this name?

17. INDIRECT EFFECT zWhat molecule to you think radiation hits? zMost interactions occur here zForms free radicals which are chemical components that damage cells zFree radicals are a result of radiolysis of water

18. FRACTIONATION zDividing a dose of radiation into small amounts over a given time

19. PROTRACTED DOSE zDose delivered continuously but at a lower rate