1. Tutorial endocrine pancreas Dr.Mohammed Sharique

2. A patient in hyperkalemic renal failure is given an infusion of glucose and insulin. The actions of insulin include which of the following? a. Converting glycogen to glucose b. Stimulating gluconeogenesis c. Increasing plasma amino acid concentration d. Enhancing potassium entry into cells

3. A 20-year-old diabetic male forgets to take his insulin prior to the start of the National Collegiate Athletic Association (NCAA) swimming championships. In which of his tissues Insulin-independent glucose uptake will occur? Why

4. A 59-year-old man is brought to his physician’s office by his wife. She reports that he has been weak, nauseated, and urinates frequently. She has also noticed a fruity odor on her husband’s breath. A urine sample is strongly positive for ketones and the finger-stick glucose is high(glucometer), leading to a presumptive bedside diagnosis of ---------------? DIABETIC KETOACIDOSIS As a result of insulin deficiency,which of the following will most likely occur? a. Increased cellular uptake of glucose c. Enhanced glucose uptake and use except by brain tissue d. Decreased fatty acid release from adipose tissue e. Increase ketogenesis

5. A researcher studying type 2 Diabetes mellitus is inducing insulin resistance in normal mice. Which of the following types of inhibitors would be effective in producing this effect? Tyrosine kinase

6. A 25-year-old woman with type 1 diabetes comes to the emergency department complaining of thirst frequent urination, and weakness. She feels “lightheaded” when she stands. Because of nausea and vomiting after a meal in a restaurant the previous day, she stopped eating and taking her insulin. On examination, she is dehydrated and hypotensive. Her breathing is rapid and deep. Relate the symptoms withcause Which of the following is likely to be lower than normal? Urinary urea levels Plasma levels of glucagons Plasma levels of free fatty acids Blood partial pressure of carbon dioxide Plasma acetocetate levels

7. A 40 year old women wins Ras Al Khaimah half marathon in record time Which of the following describes her hormone balance as she crosses the finish line? – Insulin high, glucagon high – Insulin high, glucagon low – Insulin low, glucagon low – Insulin low, glucagon high – Insulin equal to glucagon Which of the following is decreased in concentration in her liver? – Fructose 6-phosphate – Phosphoenolpyruvate carboxykinase – Fructose 2,6-bisphosphate – Glucose-6-phosphate – Phosphorylase