1. Human Body Orientation CHAPTER 1

2. Anatomy & Physiology Structure serves function Examples: Bone Lung Multi-tasking systems

3. Levels of Organization Chemical Elements Molecules Macromolecules Cells Tissues

4. Levels of Organization Organs Organ systems Organism

5. Positive & Negative Feedback Three elements Sensor Control center Effectors

7. Negative feedback loop Stimulus Sensor Control center Example: Temperature Regulation

10. Positive feedback Not really a loop Feed-forward Example Blood Clotting. Labor and Delivery

11. Homeostatic Imbalance Aging Body control systems become less efficient Diseases of aging? What systems are affected?

26. – Basic Biochemistry CHAPTER 2

27. Terminology Matter Mass Weight C,H,O,N make up 96% of body mass.

28. Building blocks of elements Atoms protons neutrons electrons

29. Periodic Table Chemical symbol Atomic # Mass #

30. Chemical bond formation Compounds chemical bond = attractive forces potential for forming bonds valency electrons are promiscuous

31. Types of chemical bonds Ionic Cation Anion Covalent Polar Nonpolar Hydrogen Weakest chemical bond Figure 2.6 Universal solvent

34. Rate of chem. Rx. and bond form. Temperature Particle size Concentration Catalysts (enzymes)

35. Biochemistry Organic Inorganic

36. Physiological pH = 7.4 pHPCO2HCO3- 7.453522 7.354526 7.0

38. Homeostatic Imbalance Acidosis Metabolic Respiratory Electrolyte Imbalance Severe heat stress Kidney failure Prolonged Diarrhea

39. Inorganic molecules Water Functions Temperature control Solvent Transport Chemical reactions

40. Inorganic molecules Salts Functions Make bones Conducts Stimulates Iron

41. Inorganic molecules Acids Bases

42. Organic Macromolecules Carbohydrates

43. Organic Macromolecules Carbohydrates Lipids Proteins

44. Organic Macromolecules Carbohydrates Lipids Proteins Nucleic Acids ATP

51. Summary: Inorganicvs.Organic 1. NonlivingLiving 2. Usually no CarbonCarbon central molecule 3. Ionic bondsCovalent bonds 4. Smaller moleculesLarge molecules 5. Water, salts, Carbohydrates, lipids, acids, basesproteins, nucleic acids, adenosine, phosphate