1. Norwegian Institute of Public Health Kristine Bjerve Gutzkow, Birgitte Lindeman, Trygve Danielsen An overview 23.06.2011 Division of Environmental medicine Department of Chemicals and Radiation

2. The Norwegian Institute of Public Health (NIPH in Oslo and Bergen) More than 1000 employees 23.06.2011

3. Aims of the NIPH Provide evidence based advice to the government and to the public at large Prevention of disease through –Health surveillance –Research –Advice and services 23.06.2011

4. Main areas –Infectious disease control –Environmental medicine –Epidemiology of non-communicable diseases –Mental health –Forensic medicine and drug abuse research 23.06.2011

5. Environmental Medicine We provide expert knowledge of environmental medicine: –prevent disease and health injuries caused by environmental toxicants and other hazardous factors in the environment –perform research and surveillance on environmental factors –food and water safety, research on air pollution, noise pollution. Close collaboration with other relevant institutes and authorities 23.06.2011

6. Department of Chemicals and Radiation (MIKS) Experience in regulation of chemicals (at National and European levels) Identification of chemicals posing threats to humans and/or the environment Persistent chemicals Vision: No use of potentially harmful chemicals Classification and labelling of chemicals and products

7. Our research interest Chemical and radiation threats to fertility and offspring We are active in research on agents and mechanisms relevant for: –Genotoxicity and mutagenicity –Reprotoxicity – male fertility and offspring health –Neurodevelopment –Implications of the exposome – cocktail effect

8. Close collaboration with our Directorate for the Environment (MDir) Norway is not a full member of EU! However, as an associate member we have adopted most of EU’s regulations of chemicals Pesticides REACH Biocide Directive

9. Safe use of chemicals – public health issues Population studies: –Used to monitor possible health problems when they have occurred –Associations are found, but the existence of causation is most often not known Experimental studies (in vivo and in vitro) –Provide mechanistic information –Essential for testing new substances, new products, or new treatments (drugs)

10. Thank you!